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BCG 백신 접종과 알레르기질환과의 관계

Other Titles
 The Relationship between BCG Vaccination and Allergic Diseases 
Authors
 유진호  ;  김효빈  ;  이소연  ;  박화영  ;  김우경  ;  손명현  ;  임대현  ;  심정연  ;  이수영  ;  이혜란  ;  홍수종 
Citation
 Pediatric Allergy and Respiratory Disease (소아알레르기 호흡기학회지), Vol.18(2) : 167-173, 2008 
Journal Title
 Pediatric Allergy and Respiratory Disease (소아알레르기 호흡기학회지) 
ISSN
 1225-679x 
Issue Date
2008
Keywords
BCG ; Allergic disease ; Asthma ; Children
Abstract
Purpose: An increase in the prevalence of allergic diseases in our country as well as countries with a western life style may be due to a decrease in exposure to infectious agents in the early life. The aim of this study is to identify the relationship between BCG vaccination and allergic diseases in school-aged children. Methods: A questionnaire survey was conducted on 8,378 elementary school children, in Seoul, Korea. Multiple logistic regression analysis was performed to investigate the independent relationship between BCG vaccination and allergic diseases. Results: The significant associations between BCG vaccination and diagnosis of asthma or current wheeze (adjusted OR: 0.49 [95% CI: 0.29-0.82], 0.51 [0.28-0.93], respectively), all being adjusted by confounding factors. However, there was no association between BCG vaccination and diagnosis of allergic rhinitis or atopic dermatitis, or current symptoms of allergic rhinitis or atopic dermatitis. Conclusion: These findings suggest that BCG vaccination in early childhood may prevent the development of asthma in school-aged children in Seoul, Korea
Files in This Item:
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아과학교실) > 1. Journal Papers
Yonsei Authors
Sohn, Myung Hyun(손명현) ORCID logo https://orcid.org/0000-0002-2478-487X
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/108353
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