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한국 성인 알레르기 비염 환자의 삶의 질 평가를 위한 설문지 개발 및 유용성 평가를 위한 연구

Other Titles
 Development and Validation of a Korean Allergic Rhinitis-Specific Quality of Life Questionnaire (KARQLQ) 
Authors
 정민규  ;  홍성진  ;  이수현  ;  홍수정  ;  손정우  ;  강원석  ;  이용원  ;  홍천수  ;  이정권  ;  박중원 
Citation
 Journal of Asthma, Allergy and Clinical Immunology (천식 및 알레르기), Vol.28(2) : 113-120, 2008 
Journal Title
 Journal of Asthma, Allergy and Clinical Immunology  (천식 및 알레르기) 
ISSN
 1226-8739 
Issue Date
2008
Abstract
Background: Quantitative measurement of allergic rhinitis (AR)-specific quality of life (QOL) impairment is important for the evaluation of its burden and efficacy of treatment. However, the QOL questionnaire for Korean AR has not yet been developed. Objective: The aim of this study is to develop and validate the QOL questionnaire for Korean AR patients. Method: We surveyed 22 AR-related items in 284 persistent AR patients and, based on the survey, developed an AR-specific Korean QOL questionnaire. The questionnaire consisted of 15 items and adapted 5-point scale for each item. We validated the questionnaire by comparing the QOL scores from 95 patients before and after the treatments with mometasone or levocetrizine. Result: The mean QOL score was lowered by 0.73 (0.33, 1.80) (P<0.001) in 30 patients with a definite improvement and by 0.63 (-0.33, 1.73) (P<0.001) in 29 patients with a slight improvement. However, the score was not significantly lowered in 17 patients without improvement [0.20 (0.00, 0.33), P=0.24]. The questionnaire was also highly reproducible with the value of intraclass correlation coefficient and interclass standard deviation as 0.996 (P<0.001) and 0.736, respectively. Conclusion We developed and validated a Korean allergic rhinitis QOL questionnaire, and this can be used for evaluating the efficacy of treatment modalities for AR.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Otorhinolaryngology (이비인후과학교실) > 1. Journal Papers
Yonsei Authors
Kang, Won Suk(강원석)
Park, Jung Won(박중원) ORCID logo https://orcid.org/0000-0003-0249-8749
Son, Jung Woo(손정우)
Lee, Soo Hyeon(이수현)
Lee, Yong Won(이용원)
Lee, Jeung Gweon(이정권)
Jung, Min Kyu(정민규) ORCID logo https://orcid.org/0000-0001-8281-3387
Hong, Sung Jin(홍성진) ORCID logo https://orcid.org/0000-0003-4893-039X
Hong, Soo Jung(홍수정)
Hong, Chein Soo(홍천수)
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/108342
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