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Barbiturate 혼수치료에서 환자의 동공 빛 반사의 의의

Other Titles
 The significance of papillary light reflex of patient in barbiturate coma therapy 
 조평구  ;  황 금  ;  변진수  ;  허 철  ;  홍순기  ;  정현호 
 Journal of Korean Neurotraumatology Society (대한신경손상학회지), Vol.4(2) : 57-61, 2008 
Journal Title
 Journal of Korean Neurotraumatology Society (대한신경손상학회지) 
Issue Date
Barbiturate coma therapy ; Pupillary light reflex ; Severe brain swelling
Objective : The aim of this study was to examine the significance of pupillary light reflex (PLR) during barbiturate coma therapy (BCT) against severe brain swelling. Methods : Between January 2003 and October 2007, 28 patients (traumatic brain injury: 15) underwent BCT because of maintained severe brain swelling after operation. All the patients maintained 3-6th wave per minute activity on electro-encephalography, and PLR were checked every 2 hours during BCT. The patient's performance was checked using Glasgow outcome scale (GOS) at the average 19.6 days (1-60 days) after BCT. Results :Twenty one patients had PLR at the start of BCT. Among 21 patients, 12 patient's PLR were vanished during BCT. Nine of 12 patients were dead (GOS=1), two had severe disability (GOS=2), and one stayed persistent vegetative state (GOS =3). But other nine patient's group, who showed prompt PLR continuously during BCT, got more improved GOS, compared with PLR vanished patient's group; 7 of 9 patients ranked more than GOS score 3. Conclusion :Our clinical data suggest that the maintaining prompt PLR during BCT is a positive finding to predict good outcome.
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1. College of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학교실) > 1. Journal Papers
Yonsei Authors
Jung, Hyun Ho(정현호)
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