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Who's Winning the War? Molecular Mechanisms of Antibiotic Resistance in Helicobacter pylori.
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 차정헌 | - |
dc.date.accessioned | 2015-05-19T17:30:47Z | - |
dc.date.available | 2015-05-19T17:30:47Z | - |
dc.date.issued | 2008 | - |
dc.identifier.issn | 1574-8855 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/108287 | - |
dc.description.abstract | The ability of clinicians to wage an effective war against many bacterial infections is increasingly being hampered by skyrocketing rates of antibiotic resistance. Indeed, antibiotic resistance is a significant problem for treatment of diseases caused by virtually all known infectious bacteria. The gastric pathogen Helicobacter pylori is no exception to this rule. With more than 50% of the world's population infected, H. pylori exacts a tremendous medical burden and represents an interesting paradigm for cancer development; it is the only bacterium that is currently recognized as a carcinogen. It is now firmly established that H. pylori infection is associated with diseases such as gastritis, peptic and duodenal ulceration and two forms of gastric cancer, gastric adenocarcinoma and mucosa-associated lymphoid tissue (MALT) lymphoma. With such a large percentage of the population infected, increasing rates of antibiotic resistance are particularly vexing for a treatment regime that is already fairly complicated; treatment consists of two antibiotics and a proton pump inhibitor. To date, resistance has been found to all primary and secondary lines of antibiotic treatment as well as to drugs used for rescue therapy. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 190~203 | - |
dc.relation.isPartOf | CURRENT DRUG THERAPY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Who's Winning the War? Molecular Mechanisms of Antibiotic Resistance in Helicobacter pylori. | - |
dc.type | Article | - |
dc.contributor.college | College of Dentistry (치과대학) | - |
dc.contributor.department | Dept. of Oral Biology (구강생물학) | - |
dc.contributor.googleauthor | Kathleen R. Jones | - |
dc.contributor.googleauthor | Jeong-Heon Cha | - |
dc.contributor.googleauthor | D. Scott Merrell | - |
dc.identifier.doi | 21765819 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A04007 | - |
dc.relation.journalcode | J00664 | - |
dc.identifier.eissn | 2212-3903 | - |
dc.identifier.pmid | 21765819 | - |
dc.contributor.alternativeName | Cha, Jung Heon | - |
dc.contributor.affiliatedAuthor | Cha, Jung Heon | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 3 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 190 | - |
dc.citation.endPage | 203 | - |
dc.identifier.bibliographicCitation | CURRENT DRUG THERAPY, Vol.3(3) : 190-203, 2008 | - |
dc.identifier.rimsid | 35459 | - |
dc.type.rims | ART | - |
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