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Chemical design of nanoparticle probes for high-performance magnetic resonance imaging

Authors
 Young-wook Jun  ;  Jae-Hyun Lee  ;  Jinwoo Cheon 
Citation
 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, Vol.47(28) : 5122-5135, 2008 
Journal Title
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
ISSN
 1433-7851 
Issue Date
2008
MeSH
Animals ; Humans ; Magnetic Resonance Imaging/methods* ; Magnetic Resonance Imaging/standards ; Molecular Probe Techniques ; Nanoparticles*/chemistry
Keywords
magnetic properties ; magnetic resonance imaging ; medicinal chemistry ; nanoparticles ; nanotechnology
Abstract
Synthetic magnetic nanoparticles (MNPs) are emerging as versatile probes in biomedical applications, especially in the area of magnetic resonance imaging (MRI). Their size, which is comparable to biological functional units, and their unique magnetic properties allow their utilization as molecular imaging probes. Herein, we present an overview of recent breakthroughs in the development of new synthetic MNP probes with which the sensitive and target-specific observation of biological events at the molecular and cellular levels is possible
Full Text
http://onlinelibrary.wiley.com/doi/10.1002/anie.200701674/abstract
DOI
10.1002/anie.200701674
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Lee, Jae Hyun(이재현) ORCID logo https://orcid.org/0000-0002-0760-0071
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/108028
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