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Inhibitory Effect of Ethyl Acetate Extract of White Peach Pericarp on Adipogenesis of 3T3-L1 Preadipocyte Cells
DC Field | Value | Language |
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dc.contributor.author | 김진문 | - |
dc.contributor.author | 박홍규 | - |
dc.contributor.author | 유윤정 | - |
dc.contributor.author | 정원윤 | - |
dc.contributor.author | 차정헌 | - |
dc.date.accessioned | 2015-05-19T17:21:30Z | - |
dc.date.available | 2015-05-19T17:21:30Z | - |
dc.date.issued | 2008 | - |
dc.identifier.issn | 1226-7708 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/107995 | - |
dc.description.abstract | In order to determine whether peach contains compounds to regulate adipocyte differentiation, extracts of flesh/pericarp of yellow/white peach were prepared in water, ethyl acetate (EtOAc), or n-butanol solvent and determined for effects on adipocyte differentiation in C3H10T1/2 or 3T3-L1 cells. Interestingly, none of peach extracts has statistically significant stimulatory effect on the adipocyte differentiation in C3H10T1/2. Furthermore, the presence of EtOAc extract of white peach pericarp (WPP) was found to inhibit lipid accumulation in 3T3-L1 cells both by microscopic examination of Oil Red Ostained lipid droplets and by spectrophotometric quantification of extracted stain, indicating a significant inhibitory effect on adipocyte differentiation. The inhibition of lipid accumulation was accompanied by a significant decrease in the expression levels of adipocyte molecular markers-peroxisome proliferator-activated receptor γ, CAAT enhancer binding protein α, and fatty acid-binding protein. Thus, this study determined that WPP EtOAc extract contains the inhibitory compound(s) on adipogenesis. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1327~1331 | - |
dc.relation.isPartOf | FOOD SCIENCE AND BIOTECHNOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Inhibitory Effect of Ethyl Acetate Extract of White Peach Pericarp on Adipogenesis of 3T3-L1 Preadipocyte Cells | - |
dc.type | Article | - |
dc.contributor.college | College of Dentistry (치과대학) | - |
dc.contributor.department | Dept. of Oral Biology (구강생물학) | - |
dc.contributor.googleauthor | Hong Gyu Park | - |
dc.contributor.googleauthor | Jin Moon Kim | - |
dc.contributor.googleauthor | Jung Mogg Kim | - |
dc.contributor.googleauthor | Won-Yoon Chung | - |
dc.contributor.googleauthor | Yun-Jung Yoo | - |
dc.contributor.googleauthor | Jeong-Heon Cha | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01014 | - |
dc.contributor.localId | A01771 | - |
dc.contributor.localId | A02490 | - |
dc.contributor.localId | A03676 | - |
dc.contributor.localId | A04007 | - |
dc.relation.journalcode | J00901 | - |
dc.identifier.eissn | 2092-6456 | - |
dc.identifier.pmid | Prunus persica ; peach ; obesity ; C3H10T1/2 ; 3T3-L1 | - |
dc.subject.keyword | Prunus persica | - |
dc.subject.keyword | peach | - |
dc.subject.keyword | obesity | - |
dc.subject.keyword | C3H10T1/2 | - |
dc.subject.keyword | 3T3-L1 | - |
dc.contributor.alternativeName | Kim, Jin Moon | - |
dc.contributor.alternativeName | Park, Hong Gyu | - |
dc.contributor.alternativeName | Yoo, Yun Jung | - |
dc.contributor.alternativeName | Chung, Won Yoon | - |
dc.contributor.alternativeName | Cha, Jung Heon | - |
dc.contributor.affiliatedAuthor | Kim, Jin Moon | - |
dc.contributor.affiliatedAuthor | Park, Hong Gyu | - |
dc.contributor.affiliatedAuthor | Yoo, Yun Jung | - |
dc.contributor.affiliatedAuthor | Chung, Won Yoon | - |
dc.contributor.affiliatedAuthor | Cha, Jung Heon | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 17 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 1327 | - |
dc.citation.endPage | 1331 | - |
dc.identifier.bibliographicCitation | FOOD SCIENCE AND BIOTECHNOLOGY, Vol.17(6) : 1327-1331, 2008 | - |
dc.identifier.rimsid | 50049 | - |
dc.type.rims | ART | - |
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