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소아의 하악골을 침범한 랑거한스세포 조직구 증식증의 임상적 고찰

Other Titles
 Langerhans Cell Histiocytosis in the Juvenile Mandible 
 강연희  ;  박세현  ;  서동준  ;  차인호  ;  이충국  ;  김현실  ;  김진  ;  김형준 
 Journal of Korean Association Maxillofacial Plastic Reconstructive Surgery (대한악안면성형재건외과학회지), Vol.30(6) : 577-583, 2008 
Journal Title
Journal of Korean Association Maxillofacial Plastic Reconstructive Surgery(대한악안면성형재건외과학회지)
Issue Date
Langerhans cell histiocytosis ; Histiocytosis-X ; Hand-Schuller-Christian disease ; Eosinophilic granuloma ; Letterer-Siwe disease
Langerhans cell histiocytosis (LCH) is characterized by proliferation of pathological Langerhans cells within different organs. It mainly affects children, but adult cases also occur, with an incidence rate of one to two per million.1,2) LCH results from the clonal proliferation of Langerhans cells. And its etiopathogenesis is still unknown.2,3) The hypothesis that it is a neoplastic or inflammatory disease, as well as the existence or not of immunological, viral or genetic predisposing factors, has been widely discussed in the literature, but no conclusive proof has ever been provided.4) Although lesions may appear in tissues of various origins such as skin, hypothalamus, liver, lung, or lymphoid tissue, bone is the most common site of the disease. The head and neck are affected in almost 90% of cases. The maxillary and mandibular bones are affected in 5 to 10% of cases.1,5) In our report, we present four cases of LCH in patients aged 3, 4, 7 and 9 years respectively, with primary manifestation in maxillofacial area.
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2. College of Dentistry (치과대학) > Dept. of Oral Pathology (구강병리학교실) > 1. Journal Papers
2. College of Dentistry (치과대학) > Dept. of Oral and Maxillofacial Surgery (구강악안면외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Jin(김진)
Kim, Hyun Sil(김현실) ORCID logo https://orcid.org/0000-0003-3614-1764
Yi, Choong Kook(이충국)
Cha, In Ho(차인호) ORCID logo https://orcid.org/0000-0001-8259-2190
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