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Normal Ambulatory 24-Hour Esophageal pH Values in Koreans -A Multicenter Study-

Authors
 Gwang Ha Kim  ;  Kyu Chan Huh  ;  Yong Chan Lee  ;  Kwang Jae Lee  ;  Suck Chei Choi  ;  Ki Nam Shim  ;  Jeong Hwan Kim  ;  In Seok Lee  ;  Hang Lak Lee  ;  Hwoon-Yong Jung  ;  Hyo Jin Park 
Citation
 JOURNAL OF KOREAN MEDICAL SCIENCE, Vol.23(6) : 954-958, 2008 
Journal Title
 JOURNAL OF KOREAN MEDICAL SCIENCE 
ISSN
 1011-8934 
Issue Date
2008
MeSH
Adult ; Age Factors ; Aged ; Esophageal pH Monitoring* ; Female ; Gastric Acidity Determination ; Gastroesophageal Reflux/diagnosis* ; Humans ; Hydrogen-Ion Concentration ; Korea ; Male ; Middle Aged ; Reference Values ; Sex Factors ; Time Factors
Keywords
Ambulatory 24-hr Esophageal pH Monitoring ; Gastroesophageal Reflux ; Reference Values
Abstract
Ambulatory 24-hr esophageal pH monitoring is considered the gold standard for diagnosing gastroesophageal reflux disease. The aim of this study was to establish normal values for gastroesophageal acid exposure in healthy Koreans. Fifty healthy volunteers (24 males and 26 females; mean age, 45 yr) without reflux symptoms and without reflux esophagitis or hiatal hernia on upper endoscopy underwent ambulatory 24-hr esophageal pH monitoring after esophageal manometry. The 95th percentiles for the reflux parameters were: the percent total time pH <4, 3.7%; the percent upright time pH <4, 5.7%; the percent supine time pH <4, 1.0%; the number of reflux episodes with pH <4, 76.5; the number of reflux episodes with pH <4 for >5 min, 1.5; the duration of the longest episode, 12.5 min; and the composite score, 14.2. Age and gender were not associated with any of the pH parameters. In conclusion, physiological gastroesophageal reflux occurs in healthy Koreans. These normal esophageal pH values will provide reference data for clinical and research studies in Korea
Files in This Item:
T200801569.pdf Download
DOI
10.3346/jkms.2008.23.6.954
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Park, Hyo Jin(박효진) ORCID logo https://orcid.org/0000-0003-4814-8330
Lee, Yong Chan(이용찬) ORCID logo https://orcid.org/0000-0001-8800-6906
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/107901
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