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대장의 크립토콕쿠스증 1예

Other Titles
 A Case of Colonic Cryptococcosis 
 송재천  ;  김상겸  ;  김익성  ;  정인수  ;  송영구  ;  유정식  ;  박효진 
 Korean Journal of Gastroenterology, Vol.52(4) : 255-260, 2008 
Journal Title
Korean Journal of Gastroenterology(대한소화기학회지)
Issue Date
Adult ; Amphotericin B/therapeutic use ; Antifungal Agents/therapeutic use ; Colonic Diseases/diagnosis* ; Colonic Diseases/drug therapy ; Colonic Diseases/pathology ; Colonoscopy ; Cryptococcosis/diagnosis* ; Cryptococcosis/drug therapy ; Cryptococcus neoformans* ; Female ; Fluconazole/therapeutic use ; Humans ; Injections, Intravenous ; Tomography, X-Ray Computed
Cryptococcosis ; Colon
We experienced a rare case of colonic cryptococcosis in an apparently immunocompetent individual. A 27-year-old woman admitted our hospital for intermittent melena. Initial abdominal CT scan revealed a mass lesion obstructing most of the lumen in ascending colon. Colonoscopy showed huge ulcerofungating mass in proximal ascending colon. Colonoscopic biopsy was performed and pathologic diagnosis was made as colonic cryptococcosis with positive PAS stain. Laboratory test evaluating immune status and bone marrow examination was normal. The patient was treated with intravenous amphotericin B for four weeks and six months of oral fluconazole afterwards. Follow-up abdominal CT scan and colonoscopy were taken at four weeks and seven months after the beginning of treatment. On completion of intravenous amphotericin B treatment, the mass lesion was decreased in abdominal CT and colonoscopy. After seven months, abdominal CT and colonoscopy showed near-complete resolution of the colonic lesion so the treatment ended. Cryptococcosis in a healthy individual is a rare disease and there have been only several sporadic case reports on pulmonary or central nervous system involvement. Hence, we report a case of colonic cryptococcosis in an apparently immunocompetent individual.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Park, Hyo Jin(박효진) ORCID logo https://orcid.org/0000-0003-4814-8330
Song, Young Goo(송영구) ORCID logo https://orcid.org/0000-0002-0733-4156
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