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Comparison of botulinum toxin type A injection and soft-tissue surgery to treat hip subluxation in children with cerebral palsy.

DC Field Value Language
dc.contributor.author김현우-
dc.contributor.author나동욱-
dc.contributor.author박은숙-
dc.date.accessioned2015-05-19T17:13:39Z-
dc.date.available2015-05-19T17:13:39Z-
dc.date.issued2008-
dc.identifier.issn0003-9993-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/107745-
dc.description.abstractOBJECTIVE: To compare the effects of botulinum toxin type A (BTX-A) injection into the hip adductor muscles on hip displacement with soft-tissue surgery and assess the factors related to a favorable outcome after intervention in children with bilateral spastic cerebral palsy (CP). DESIGN: Retrospective chart review with regard to radiographic findings. SETTING: University hospital. PARTICIPANTS: Children with CP (N=194). INTERVENTIONS: BTX-A injection and soft-tissue surgery into the hip adductor muscles. MAIN OUTCOME MEASURE: The Reimers hip migration percentage (MP). RESULTS: Sixty-nine children did not receive any therapeutic intervention for hip displacement, whereas 60 children underwent soft-tissue surgery and 65 children took BTX-A injection for the spasticity of their hip muscles. MP was measured on each radiograph of the pelvis. The annual change of MP was improved in both the soft-tissue surgery and BTX-A groups, whereas it worsened in the nonintervention group. The annual improvement of MP in the BTX-A group did not differ significantly from that of the soft-tissue surgery group. The improvement in hip displacement after therapeutic intervention was greater in young children and high-functioning groups compared with older children and low-functioning groups. Hip displacement was progressive in the severely hip subluxated group despite therapeutic intervention. CONCLUSIONS: Comparable effects of BTX-A injection to soft-tissue surgery in our study suggest that BTX-A injection, if timely reinjected, may replace soft-tissue surgery as a prophylactic procedure against progressive hip subluxation or dislocation in children. Age at intervention, functional level, and initial MP before therapeutic intervention were the factors affecting the outcomes.-
dc.description.statementOfResponsibilityopen-
dc.format.extent2108~2113-
dc.relation.isPartOfARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHBotulinum Toxins, Type A/therapeutic use*-
dc.subject.MESHCerebral Palsy/complications-
dc.subject.MESHCerebral Palsy/rehabilitation*-
dc.subject.MESHChild, Preschool-
dc.subject.MESHFemale-
dc.subject.MESHHip Dislocation/prevention & control*-
dc.subject.MESHHip Joint*-
dc.subject.MESHHumans-
dc.subject.MESHInfant-
dc.subject.MESHJoint Instability/diagnostic imaging-
dc.subject.MESHJoint Instability/drug therapy*-
dc.subject.MESHJoint Instability/surgery*-
dc.subject.MESHMale-
dc.subject.MESHMuscle Spasticity-
dc.subject.MESHMuscle, Skeletal/surgery-
dc.subject.MESHNeuromuscular Agents/therapeutic use*-
dc.subject.MESHRadiography-
dc.subject.MESHRetrospective Studies-
dc.titleComparison of botulinum toxin type A injection and soft-tissue surgery to treat hip subluxation in children with cerebral palsy.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Rehabilitation Medicine (재활의학)-
dc.contributor.googleauthorEun Joo Yang-
dc.contributor.googleauthorDong-wook Rha-
dc.contributor.googleauthorHyun Woo Kim-
dc.contributor.googleauthorEun Sook Park-
dc.identifier.doi10.1016/j.apmr.2008.04.019-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01124-
dc.contributor.localIdA01230-
dc.contributor.localIdA01611-
dc.relation.journalcodeJ00230-
dc.identifier.eissn1532-821X-
dc.identifier.pmid18996239-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S0003999308005534-
dc.subject.keywordBotulinum toxin type A-
dc.subject.keywordCerebral palsy-
dc.subject.keywordRehabilitation-
dc.contributor.alternativeNameKim, Hyun Woo-
dc.contributor.alternativeNameRha, Dong Wook-
dc.contributor.alternativeNamePark, Eun Sook-
dc.contributor.affiliatedAuthorKim, Hyun Woo-
dc.contributor.affiliatedAuthorRha, Dong Wook-
dc.contributor.affiliatedAuthorPark, Eun Sook-
dc.rights.accessRightsnot free-
dc.citation.volume89-
dc.citation.number11-
dc.citation.startPage2108-
dc.citation.endPage2113-
dc.identifier.bibliographicCitationARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION, Vol.89(11) : 2108-2113, 2008-
dc.identifier.rimsid55300-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Orthopedic Surgery (정형외과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Rehabilitation Medicine (재활의학교실) > 1. Journal Papers

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