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Is gastrectomy mandatory for all residual or recurrent gastric cancer following endoscopic resection? A large-scale Korean multi-center study

Authors
 KYO YOUNG SONG  ;  WOO JIN HYUNG  ;  HYUNG HO KIM  ;  SANG UK HAN  ;  GYU SEOK CHO  ;  SEUNG WAN RYU  ;  HYUK JOON LEE  ;  MIN CHAN KIM 
Citation
 JOURNAL OF SURGICAL ONCOLOGY, Vol.98(1) : 6-10, 2008 
Journal Title
JOURNAL OF SURGICAL ONCOLOGY
ISSN
 0022-4790 
Issue Date
2008
MeSH
Adult ; Aged ; Aged, 80 and over ; Carcinoma/pathology* ; Carcinoma/secondary ; Carcinoma/surgery* ; Female ; Follow-Up Studies ; Gastrectomy* ; Gastroscopy ; Guideline Adherence/standards ; Humans ; Laparoscopy ; Lymph Node Excision ; Lymphatic Metastasis ; Male ; Middle Aged ; Neoplasm Recurrence, Local/pathology ; Neoplasm Recurrence, Local/surgery* ; Neoplasm, Residual/pathology ; Neoplasm, Residual/surgery* ; Practice Guidelines as Topic ; Prospective Studies ; Reoperation ; Stomach Neoplasms/pathology* ; Stomach Neoplasms/surgery* ; Treatment Outcome
Keywords
clinicopathological features ; residual ; recurrent ; endoscopic resection ; laparoscopic gastrectomy
Abstract
BACKGROUND AND OBJECTIVES: To clarify optimal treatment guidelines for residual or local recurrence after endoscopic resection (ER). METHODS: Eighty-six patients underwent gastrectomy due to incomplete ER and local recurrence after ER. The pathological findings of ER and gastrectomy specimens were analyzed. RESULTS: The cause of gastrectomy was categorized into five groups; submucosal (sm) invasion without margin involvement, positive margin, margin not evaluable, high risk of lymph node metastasis and local recurrence after ER. According to the pathological findings of gastrectomy specimens, remnant cancer and lymph node metastases were found in 56 (65.1%) and in 5 patients (5.8%), respectively. At 10 gastrectomy specimens which were sm invasion without margin involvement, the scattered residual cancer cells were found around the ulcer scar in 2 (20%) patients. In 11 of 44 margin involvement specimens, no residual cancer or lymph node metastasis was found. In patients with local recurrence, mean duration from ER to surgery was 14.8 months, and 19% of patients were found to have sm or deeper depth of invasion. CONCLUSION: Gastrectomy with lymph node dissection should be performed in patients with sm invasion with or without margin involvement. However, minimal approach other than gastrectomy could further be applied to selected patients.
Full Text
http://onlinelibrary.wiley.com/doi/10.1002/jso.21074/abstract
DOI
10.1002/jso.21074
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
Hyung, Woo Jin(형우진) ORCID logo https://orcid.org/0000-0002-8593-9214
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/107663
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