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한국형 양극성 장애 약물치료 알고리듬 2006(Ⅵ)-다른 치료 지침들과의 비교

Other Titles
 Korean Medication Algorithm for Bipolar Disorder 2006(Ⅵ):Comparisons with Other Treatment Guidelines 
 윤보현  ;  박원명  ;  배승오  ;  전덕인  ;  민경준  ;  신영철  ;  조현상  ;  정상근  ;  하규섭  ;  서정석  ;  김원  ;  이은  ;  권준수 
 Korean Journal of Psychopharmacology (대한정신약물학회지), Vol.19(1) : 5-18, 2008 
Journal Title
Korean Journal of Psychopharmacology(대한정신약물학회지)
Issue Date
Bipolar disorder ; Pharmacotherapy ; Treatment guideline ; Algorithm
The Korean Medication Algorithm Project for Bipolar Disorder (KMAP-BP) was developed in 2002 and revised in 2006. The aim of this study was to compare the KMAP-BP 2006 with other recently published treatment guidelines for bipolar disorder. We conducted a systematic review of the six most recently published guidelines and treatment algorithms for bipolar disorder to compare the similarities and differences between these guidelines and the KMAPBP 2006. Most treatment guidelines had similarities in their treatment options. The guidelines generally advocated atypical antipsychotics as first-line treatment in the manic phase and lamotrigine in the depressive phase. While lithium and divalproex were commonly used as mood stabilizers in the manic phase, divalproex was recommended in mixed or dysphoric mania. Mood stabilizers or atypical antipsychotics were selected as first-line treatment in maintenance. Some guidelines were more concerned about special clinical situations such as pregnancy, obesity, metabolic syndrome, and elderly patients, which were not described in the KMAP-BP 2006. Our findings suggest that themedication strategies for bipolar disorder are based on data from recent studies and clinical experiences. Useful information and a rationale for making sequential treatment decisions can be provided by critically reviewing the treatment guidelines. The treatment algorithms and guidelines are not substitutes for clinical judgment, but can serve as critical references to complement individual clinical assessments.
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1. College of Medicine (의과대학) > Dept. of Psychiatry (정신과학교실) > 1. Journal Papers
Yonsei Authors
Cho, Hyun Sang(조현상) ORCID logo https://orcid.org/0000-0003-1019-9941
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