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Solitary skull metastasis as initial manifestation of hepatocellular carcinoma.

Authors
 Yu Shik Shim  ;  Jung Yong Ahn  ;  Jun Hyung Cho  ;  Kyu Sung Lee 
Citation
 World Journal of Surgical Oncology, Vol.6 : 66, 2008 
Journal Title
 World Journal of Surgical Oncology 
ISSN
 1477-7819 
Issue Date
2008
MeSH
Aged ; Biopsy, Needle ; Carcinoma, Hepatocellular/pathology* ; Carcinoma, Hepatocellular/therapy ; Chemoembolization, Therapeutic ; Humans ; Liver Neoplasms/pathology* ; Liver Neoplasms/therapy ; Magnetic Resonance Imaging ; Male ; Skull/pathology* ; Skull Neoplasms/diagnosis* ; Skull Neoplasms/secondary* ; Skull Neoplasms/surgery ; Treatment Outcome
Keywords
Bone Metastasis ; Primary Cancer ; Transarterial Chemoembolization ; Percutaneous Needle Biopsy ; Extracranial Metastasis
Abstract
BACKGROUND: A solitary skull metastasis from hepatocellular carcinoma (HCC) prior to diagnosis of the primary tumor without liver dysfunction is a very rare event. CASE PRESENTATION: A 71-year-old male, without known liver disease, presented to our institution with a palpable occipital scalp mass. On brain magnetic resonance imaging (MRI), a highly enhanced and osteolytic skull tumor was observed. The histological diagnosis obtained from the percutaneous needle biopsy was a cranial metastasis from HCC. The metastatic tumor was removed via occipital craniectomy, and the two primary liver mass lesions were subsequently treated by transarterial chemoembolization. CONCLUSION: An isolated skull metastasis may be the sole initial presentation of HCC. Early diagnosis is essential in order to treat the primary disease. A skull metastasis from HCC should be considered in the differential diagnosis in patients with subcutaneous scalp mass and osteolytic defects on X-ray
Files in This Item:
T200801106.pdf Download
DOI
10.1186/1477-7819-6-66
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학교실) > 1. Journal Papers
Yonsei Authors
Shim, Yu Shik(심유식)
Ahn, Jung Yong(안정용)
Lee, Kyu Sung(이규성)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/107382
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