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임상적 비기능성 뇌하수체 종양의 미세현미경적 가성피막의 제거

Other Titles
 Microsurgical Pseudocapsule Resection of Clinically Nonfunctioning Pituitary Tumors 
 Byeong Woo Kim  ;  Yu Shik Shim  ;  Jong Hee Chang  ;  Jung Yong Ahn  ;  Sun Ho Kim 
 Journal of Korean Skull Base Society (대한두개저외과학회지), Vol.3(1) : 21-25, 2008 
Journal Title
 Journal of Korean Skull Base Society (대한두개저외과학회지) 
Issue Date
Objective : The aim of this study was to investigate the precise histological characteristics of the boundary, using surgical specimens from patients who underwent intensive resection of “microsurgical pseudocapsule”of clinically non-functioning pituitary tumors (CNPTs). Furthermore, we compared the remission rate of CNPTs between subjects with (Group 1) and without (Group 2) intensive resection of microsurgical pseudocapsule in order to correlate the histological complete resection and endocrinological remission. Patients and Methods : Between January 2000 and December 2007, 113 patients underwent intensive microsurgical dissection during the transsphenoidal surgery in one hospital (Group 1). In the other hand, 24 patients underwent conventional subcapsular resection without intentionally removing the microsurgical pseudocapsule in another hospital (Group 2). Results : The overall surgical remission rate in Group 1 with intensive resection of microsurgical pseudocapsule were statistically higher than the rates in Group 2 (without intensive resection of microsurgical pseudocapsule) (p=0.032). However, there were no statistical differences in postoperative hormonal function change between Group 1 and 2. Conclusions : Our results indicate that aggressive resection of psuedocapsules increases the cure rate without aggravating pituitary function
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Sun Ho(김선호) ORCID logo https://orcid.org/0000-0003-0970-3848
Shim, Yu Shik(심유식)
Ahn, Jung Yong(안정용)
Chang, Jong Hee(장종희)
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