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결핵 환자에서 Rifampin에 의한 Henoch-Shonlein Purpura 1예

Other Titles
 A Case of Henoch-Shonlein Purpura Caused by Rifampin 
 김혜련  ;  박병훈  ;  손지영  ;  정지예  ;  안정련  ;  정윤숙  ;  임주은  ;  정주원  ;  문지애  ;  변민광  ;  김영삼  ;  김세규  ;  장 준  ;  이광길  ;  박무석 
 Tuberculosis and Respiratory Diseases, Vol.65(2) : 116-120, 2008 
Journal Title
 Tuberculosis and Respiratory Diseases 
Issue Date
Rifampin is one of the first line drugs for treating tuberculosis, but it might be associated with serious adverse effects, including renal failure. We report here on a case of a 57-year-old patient who developed Henoch-Shonlein purpura during antituberculosis therapy that included rifampin. The patient converted to negative on the AFB smear for tuberculosis two weeks after the initial administration of antituberculosis medication. After treatment for 60 days, this patient was diagnosed with Henoch-Shonlein purpura by the purpura lesion on the lower legs, the leukocytoclastic vasculitis, the renal impairment and the pathological examination. After stopping rifampin, the skin lesions disappeared in about 10 days and his renal function gradually improved. This case study showed that Henoch-Schonlein purpura can be caused by rifampin during antituberculosis therapy and we recommend that the use of rifampin should be restrained when clinical symptoms of Henoch-Shonlein purpura are observed
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
Yonsei Authors
김세규(Kim, Se Kyu)
김영삼(Kim, Young Sam) ORCID logo https://orcid.org/0000-0001-9656-8482
김혜련(Kim, Hye Ryun) ORCID logo https://orcid.org/0000-0002-1842-9070
문지애(Moon, Ji Ae)
박무석(Park, Moo Suk) ORCID logo https://orcid.org/0000-0003-0820-7615
박병훈(Park, Byung Hoon)
변민광(Byun, Min Kwang) ORCID logo https://orcid.org/0000-0003-1525-1745
손지영(Son, Ji Young)
안정련(Ahn, Jung Ryun)
이광길(Lee, Kwang Gill)
임주은(Lim, Ju Eun)
장준(Chang, Joon) ORCID logo https://orcid.org/0000-0003-4542-6841
정윤숙(Jung, Yoon Suk)
정주원(Chung, Joo Won)
정지예(Jung, Ji Ye) ORCID logo https://orcid.org/0000-0003-1589-4142
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