3 245

Cited 43 times in

Isolated paraaortic lymph-node recurrence after the curative resection of colorectal carcinoma

Authors
 BYUNG SOH MIN  ;  NAM KYU KIM  ;  SEUNG KOOK SOHN  ;  CHANG HWAN CHO  ;  KANG YOUNG LEE  ;  SEUNG HYUK BAIK 
Citation
 JOURNAL OF SURGICAL ONCOLOGY, Vol.97(2) : 136-140, 2008 
Journal Title
 JOURNAL OF SURGICAL ONCOLOGY 
ISSN
 0022-4790 
Issue Date
2008
MeSH
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor/blood ; Carcinoembryonic Antigen/blood ; Carcinoma/surgery* ; Chemotherapy, Adjuvant ; Colectomy* ; Colonic Neoplasms/surgery* ; Female ; Follow-Up Studies ; Humans ; Lymph Node Excision ; Lymph Nodes/pathology* ; Lymphatic Metastasis/pathology ; Male ; Middle Aged ; Neoplasm Recurrence, Local/pathology* ; Neoplasm Staging ; Prognosis ; Radiotherapy, Adjuvant ; Rectal Neoplasms/surgery* ; Survival Rate ; Tomography, X-Ray Computed
Keywords
paraaortic lymph-node recurrence ; locoregional recurrence ; colorectal cancer
Abstract
BACKGROUND AND OBJECTIVES: Isolated paraaortic lymph-node recurrence (IPLR) after curative surgery for colorectal carcinoma is rare and no previous report has specifically addressed this type of recurrence. We investigated the clinical features of IPLR and analyzed prognostic factors. METHODS: Of 2,916 patients who underwent curative surgery for colorectal carcinoma, IPLR was identified in 38 patients (1.3%). The clinical features and prognostic factors of these patients were analyzed. RESULTS: IPLR was first detected by increased serum carcinoembryonic antigen (CEA) levels (63.2%) or by routine follow-up computed tomography (CT) (36.8%). Curative resection of IPLR was performed in six patients (15.8%). A total of 19 patients (50.0%) received chemoradiation therapy and 13 patients (34.2%) received chemotherapy only. The median survival from IPLR was 13 months (range: 5-60 months). The median survival time from IPLR for the resected patients was 34 months, whereas it was 12 months for those who did not undergo resection (P = 0.034). The factors associated with the prognosis were histological grade (P = 0.003), location (P = 0.032), and resection of IPLR (P = 0.034). CONCLUSIONS: IPLR after curative surgery for colorectal carcinoma is rare. Although it is generally associated with poor prognosis, better survival might be achieved through curative resection in selected cases.
Full Text
http://onlinelibrary.wiley.com/doi/10.1002/jso.20926/abstract
DOI
10.1002/jso.20926
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Nam Kyu(김남규) ORCID logo https://orcid.org/0000-0003-0639-5632
Min, Byung Soh(민병소) ORCID logo https://orcid.org/0000-0003-0180-8565
Baik, Seung Hyuk(백승혁) ORCID logo https://orcid.org/0000-0003-4183-2332
Sohn, Seung Kook(손승국)
Lee, Kang Young(이강영)
Cho, Chang Hwan(조장환)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/106795
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse