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Visceral fat thickness predicts fatty liver in Koreans with type 2 diabetes mellitus

 Hai Jin Kim  ;  Min Ho Cho  ;  Jong Suk Park  ;  Ji Sun Nam  ;  Eun Seok Kang  ;  Chul Woo Ahn  ;  Bong Soo Cha  ;  Eun Jig Lee  ;  Sung Kil Lim  ;  Kyung Rae Kim  ;  Hyun Chul Lee  ;  Kap Bum Huh 
 JOURNAL OF KOREAN MEDICAL SCIENCE, Vol.23(2) : 256-261, 2008 
Journal Title
Issue Date
Aged ; Aorta/pathology ; Cohort Studies ; Diabetes Complications/diagnosis* ; Diabetes Mellitus, Type 2/diagnosis* ; Diabetes Mellitus, Type 2/pathology ; Fatty Liver/complications* ; Fatty Liver/diagnosis* ; Female ; Humans ; Intra-Abdominal Fat/pathology* ; Male ; Middle Aged ; Models, Statistical ; Odds Ratio ; ROC Curve ; Sensitivity and Specificity
Visceral Fat Thickness, Fatty Liver, Type 2 Diabetes Mellitus
Our aim was to study whether visceral adiposity is a predictor of diabetic fatty liver in Korean type 2 diabetes mellitus. In this study, abdominal ultrasonography was used to assess the presence of fatty liver in 1,898 patients with type 2 diabetes. We measured visceral fat thickness by high-resolutional ultrasonography and insulin resistance by Kitt. Half of the cohort had a fatty liver (50.2%). High visceral fat thickness had the highest odds ratio for developing fatty liver in both sexes (odds ratio [S.D]: 3.14 [2.24-4.69], p<0.00 in male, 2.84 [2.04-3.93], p<0.00 in female). In addition, visceral fat thickness of 42.45 and 37.7 mm in men and women, respectively, were chosen as the discriminating value to predict the presence of fatty liver with a sensitivity of 71% and 73% and a specificity of 70% and 70% in men and women, respectively. The area under the receiver-operating characteristics curve was 0.759 in men and 0.764 in women. Therefore we could conclude that the degree of visceral adiposity predicts the presence of fatty liver type 2 diabetes mellitus, whether centrally obese or not, suggesting that hepatic fat accumulation in a diabetic fatty liver may be influenced by visceral fat accumulation regardless of waist circumference
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1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kang, Eun Seok(강은석) ORCID logo https://orcid.org/0000-0002-0364-4675
Kim, Kyung Rae(김경래)
Kim, Hae Jin(김혜진)
Nam, Ji Sun(남지선) ORCID logo https://orcid.org/0000-0001-8655-5258
Park, Jong Suk(박종숙) ORCID logo https://orcid.org/0000-0002-5385-1373
Ahn, Chul Woo(안철우) ORCID logo https://orcid.org/0000-0003-3733-7486
Lee, Eun Jig(이은직) ORCID logo https://orcid.org/0000-0002-9876-8370
Lee, Hyun Chul(이현철)
Lim, Sung Kil(임승길)
Cho, Min Ho(조민호)
Cha, Bong Soo(차봉수) ORCID logo https://orcid.org/0000-0003-0542-2854
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