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Magnetic dispersion of the late repolarization in Brugada syndrome.

Authors
 Boyoung Joung  ;  Kiwoong Kim  ;  Yong-Ho Lee  ;  Hyukchan Kwon  ;  Hyun Kyoon Lim  ;  Tae-Uen Kim  ;  Young-Guk Ko  ;  Moonhyoung Lee  ;  Namsik Chung  ;  Sungsoon Kim 
Citation
 Circulation Journal, Vol.72(1) : 94-101, 2008 
Journal Title
 Circulation Journal 
ISSN
 1346-9843 
Issue Date
2008
MeSH
Adult ; Aged ; Brugada Syndrome/diagnosis* ; Bundle-Branch Block/diagnosis ; Case-Control Studies ; Diagnosis, Differential ; Female ; Heart Conduction System/physiopathology ; Humans ; Magnetocardiography/methods* ; Magnetocardiography/standards ; Male ; Middle Aged
Keywords
Brugada syndrome ; Bundle branch block ; Depolarization ; Repolarization ; Magnetic dispersion ; Magnetocardiography
Abstract
BACKGROUND: Magnetocardiography (MCG) is a new noninvasive modality for recording cardiac depolarization and repolarization and was used in the present study to evaluate abnormalities in patients with Brugada syndrome (BS). METHODS AND RESULTS: The MCG findings of 10 BS, 21 right bundle branch block (RBBB), and 34 normal patients were compared. On the horizontal spatiotemporal activation graph (STAG), the r' waves were more frequently located on the right side in the RBBB than in the normal (p=0.001) or BS groups (p=0.001). The maximum current angles of the r' wave fell into the northwest axis in all BS patients as compared to having a right axis deviation in 19 of 21 RBBB patients (90.4%, p=0.001). In the magnetic field and current density vector maps during late repolarization, the BS group had a non-dipole pattern more frequently and a higher number of poles compared with the normal (p=0.001) and RBBB groups (p=0.001). CONCLUSIONS: During depolarization, the horizontal STAG location and maximum current angle of the r' wave were beneficial in differentiating BS from RBBB and normal. The magnetic dispersion was a more frequently observed finding in BS patients than in RBBB and normal patients during late repolarization.
Files in This Item:
T200800519.pdf Download
DOI
18159107
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Ko, Young Guk(고영국) ORCID logo https://orcid.org/0000-0001-7748-5788
Kim, Sung Soon(김성순)
Lee, Moon Hyoung(이문형) ORCID logo https://orcid.org/0000-0002-7268-0741
Chung, Nam Sik(정남식)
Joung, Bo Young(정보영) ORCID logo https://orcid.org/0000-0001-9036-7225
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/106706
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