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Witch hazel(Hamamelis virginiana)의 구강병원균에 대한 항균 효과

Other Titles
 The Anti-Bacterial Effect of Witch Hazel(Hamamelis virginiana) on Oral Pathogens 
Authors
 류성용  ;  안형준  ;  권정승  ;  박주현  ;  김재영  ;  최종훈 
Citation
 Journal of Korean Academy of Oral Medicine (대한구강내과학회지), Vol.33(2) : 159-166, 2008 
Journal Title
 Journal of Korean Academy of Oral Medicine  (대한구강내과학회지) 
ISSN
 1225-0627 
Issue Date
2008
Abstract
An ideal anti-bacterial medication for oral infection requires selective effect on pathogens causing dental caries and periodontal disease but not on normal flora. In addition, it should be less toxic for human and even for environment. This study was to seek such a natural anti-bacterial medication and thus anti-bacterial effect of Hamamelis virginiana was evaluated. Many recent researches on the anti-bacterial effect of natural plant extract and essential oil have reported that natural products can be used as medication for prevention and restrainment of dental caries, halitosis and periodontitis. It has been also reported that Hamamelis virginiana has anti-bacterial effect on Porphyromonas gingivalis, Fusobacterium nucleatum, Capnocytophaga gingivalis, Veilonella parvula, Eikenella corrodens, Peprostreptococcus micros, and Actinomyces odontolyticus. This study evaluated anti-bacterial effect of Hamamelis virginiana on Streptoccoccus mutans, Haemophylus actinomycetemcomitans, and Klebsiella pneumoniae to expand its anti-bacterial effect on other important oral pathogens and eventually to develop its oral care products or apply to clinical purpose. In this study, anti-bacterial tests for antibiotic disk susceptibility, minimal inhibitory concentration and minimal bactericidal concentration were performed to evaluate anti-bacterial effect of Hamamelis virginiana against Streptoccoccus mutans, Haemophylus actinomycetemcomitans, and Klebsiella pneumoniae. The results showed that Hamamelis virginiana has anti-bacterial effect on all pathogen strains tested in this study and furthermore Hamamelis virginiana possesses bactericidal effect other than bacteriostatic effect on Streptoccoccus mutans, Haemophylus actinomycetemcomitans, Klebsiella pneumoniae. This study indicates that a natural anti-bacterial medication for oral diseases can be developed using Hamamelis virginiana
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Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Orofacial Pain and Oral Medicine (구강내과학교실) > 1. Journal Papers
Yonsei Authors
권정승(Kwon, Jeong Seung) ORCID logo https://orcid.org/0000-0003-4584-7355
안형준(Ahn, Hyoung Joon)
최종훈(Choi, Jong Hoon) ORCID logo https://orcid.org/0000-0003-3211-3619
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/106640
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