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심폐우회로 이탈 후 발생한 혈관마비 증후군에서 methylene blue의 사용 : 증례보고

Other Titles
 Methylene Blue for Vasoplegic Syndrome after Cardiopulmonary Bypass - A case report - 
Authors
 이지연  ;  이민휘  ;  이종화 
Citation
 KOREAN JOURNAL OF ANESTHESIOLOGY, Vol.54(6) : 677-681, 2008 
Journal Title
 KOREAN JOURNAL OF ANESTHESIOLOGY 
ISSN
 2005-6419 
Issue Date
2008
Keywords
cardiac surgery ; methylene blue ; vasoplegic syndrome
Abstract
Vasoplegic syndrome (VS) occurs in 8-10% of patients following cardiac surgery and is associated with increased morbidity and mortality. Nitric oxide and guanylate cyclase play an important role in this response. Methylene blue, an inhibitor of guanylate cyclase, has recently been advocated as an adjunct in the treatment of catecholamine-refractory VS. We experienced a case of VS after aortic arch replacement surgery, presenting severe hypotension refractory to high-dose norepinephrine and vasopressin. Administration of methylene blue 100 mg led to immediate recovery of arterial pressure. We report this case and review the role of methylene blue in the treatment of catecholamine-refractory VS
Files in This Item:
T200800018.pdf Download
DOI
10.4097/kjae.2008.54.6.677
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers
Yonsei Authors
Lee, Jong Wha(이종화)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/106142
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