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측두하악관절 장애 환자에서 관절원판후조직의 에스트로겐 수용체(ER)의 단백 발현

Other Titles
 EXPRESSION OF ESTROGEN RECEPTORS IN RETRODISCAL TISSUE OF THE TEMPOROMANDIBULAR JOINT DISORDER PATIENTS 
Authors
 김종윤  ;  임재형  ;  박광호  ;  김형곤  ;  허종기 
Citation
 Journal of the Korean Association of Oral and Maxillofacial Surgeons (대한구강악안면외과학회지), Vol.35(6) : 403-410, 2009 
Journal Title
 Journal of the Korean Association of Oral and Maxillofacial Surgeons  (대한구강악안면외과학회지) 
ISSN
 1225-1585 
Issue Date
2009
Abstract
Those composing temporomandibular joint (TMJ) complex such as the temporal bone, the disc and the mandibular condyle perform their own functions with organic relation. The retrodiscal tissue is the main area of pain induction and contributes to compositional change of synovial fluid. If displacement of the disc lasts long time, not only adaptive changes, but also destructive or degenerative changes may happen. It was reported that these changes and symptoms appear mostly to female rather than male and especially, in the case of patients suffering from TMJ disorder, a large quantity of female sex hormone is found in the joint synovium. And that may play a role in bone resorption and inflammation. Also, the frequency and the intensity of pain perception for female is reported to be much more than for male. In this study, we investigated the expression extents of estrogen receptors (ER) and progesteron receptors (PR) in retrodiscal tissue with immunohistochemistry among the patients received TMJ surgery and compared with MRI findings and surgical findings. We report the relations between the expression of ER in retrodiscal tissue and the pathological change in TMJ, such as inflammation, internal derangement and osteoarthritis
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2. College of Dentistry (치과대학) > Dept. of Oral and Maxillofacial Surgery (구강악안면외과학교실) > 1. Journal Papers
Yonsei Authors
김형곤(Kim, Hyung Gon)
박광호(Park, Kwang Ho)
임재형(Lim, Jae Hyung)
허종기(Huh, Jong Ki) ORCID logo https://orcid.org/0000-0002-7381-3972
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/105966
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