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Left atrial strain as predictor of successful outcomes in catheter ablation for atrial fibrillation: a two-dimensional myocardial imaging study.

 Hye Jin Hwang  ;  Eui-Young Choi  ;  Sang Jae Rhee  ;  Boyoung Joung  ;  Byung-Ho Lee  ;  Sang-Hee Lee  ;  Jaedeok Kim  ;  Moon-Hyoung Lee  ;  Yangsoo Jang  ;  Namsik Chung  ;  Sung Soon Kim 
 Journal of Interventional Cardiac Electrophysiology, Vol.26(2) : 127-132, 2009 
Journal Title
 Journal of Interventional Cardiac Electrophysiology 
Issue Date
Atrial Fibrillation/diagnostic imaging* ; Atrial Fibrillation/surgery* ; Catheter Ablation/methods* ; Echocardiography/methods* ; Elastic Modulus ; Elasticity Imaging Techniques/methods* ; Female ; Heart Atria/diagnostic imaging* ; Humans ; Male ; Middle Aged ; Prognosis ; Reproducibility of Results ; Sensitivity and Specificity ; Treatment Outcome
Atrial fibrillation ; Ablation ; Strain
BACKGROUND: The objective of this study was to investigate atrial myocardial properties through two-dimensional (2D) myocardial imaging in patients with atrial fibrillation (AF) and its predictive role for recurrence after catheter ablation. METHODS AND RESULTS: Echocardiographic examinations were performed in 40 patients with paroxysmal AF before catheter ablation and 40 age- and gender-matched healthy control subjects. Using a software package, bidimensional acquisitions were analyzed to measure longitudinal strain and strain rate for the left atrium (LA). Systolic strain and strain rate in all eight segments, and its average values, were significantly reduced in AF patients compared to controls. During 9 months of follow-up after catheter ablation for AF, 11 of 40 AF patients had AF recurrence. AF recurrence was associated with gender, LA volume index, and average values of systolic strain and strain rate. By multivariate analysis, only average strain was an independent predictor of AF recurrence (OR = 0.88, 95% CI 0.79-0.98, p = 0.018). CONCLUSIONS: Lower systolic strain of LA was strongly associated with recurrence after catheter ablation. Thus, diverse adjunctive ablation strategies should be considered to reduce recurrence in patients with lower systolic strain
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1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Sung Soon(김성순)
Kim, Jae Deok(김재덕)
Lee, Moon Hyoung(이문형) ORCID logo https://orcid.org/0000-0002-7268-0741
Lee, Byung Ho(이병호)
Lee, Sang Jae(이상재)
Lee, Sang Hee(이상희)
Jang, Yang Soo(장양수) ORCID logo https://orcid.org/0000-0002-2169-3112
Chung, Nam Sik(정남식)
Joung, Bo Young(정보영) ORCID logo https://orcid.org/0000-0001-9036-7225
Choi, Eui Young(최의영) ORCID logo https://orcid.org/0000-0003-3732-0190
Hwang, Hye Jin(황혜진)
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