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Clinical spectrum of reflux esophagitis among 25,536 Koreans who underwent a health check-up: a nationwide multicenter prospective, endoscopy-based study

Authors
 Ki-Nam Shim  ;  Su Jin Hong  ;  Jae Kyu Sung  ;  Kyung Sik Park  ;  Seong-Eun Kim  ;  Hyun-Shin Park  ;  J Young Sun Kim  ;  Seon Hee Lim  ;  Chung Hyeon Kim  ;  Min Jung Park  ;  Jeong Yoon Yim  ;  Kyung Ran Cho  ;  Donghee Kim  ;  Seun Ja Park  ;  Sam-Ryong Jee  ;  Jin Il Kim  ;  Joon Yong Park  ;  Geun Am Song  ;  Hwoon-Yong Jung  ;  Yong Chan Lee  ;  Jae Gyu Kim  ;  Jae J. Kim  ;  Nayoung Kim  ;  Soo-Heon Park  ;  Hyun Chae Jung  ;  In-Sik Chung 
Citation
 JOURNAL OF CLINICAL GASTROENTEROLOGY, Vol.43(7) : 632-638, 2009 
Journal Title
 JOURNAL OF CLINICAL GASTROENTEROLOGY 
ISSN
 0192-0790 
Issue Date
2009
MeSH
Asian Continental Ancestry Group ; Endoscopy, Gastrointestinal/methods* ; Esophagitis, Peptic/diagnosis* ; Esophagitis, Peptic/epidemiology ; Esophagitis, Peptic/physiopathology ; Gastroesophageal Reflux/diagnosis* ; Gastroesophageal Reflux/epidemiology ; Gastroesophageal Reflux/physiopathology ; Humans ; Korea/epidemiology ; Prevalence ; Prospective Studies ; Sex Factors ; Surveys and Questionnaires
Keywords
reflux esophagitis ; endoscopy ; reflux symptom
Abstract
BACKGROUND: Gastroesophageal reflux is a commonly encountered condition, but detailed data on reflux symptoms in Asian countries are lacking. GOALS: To evaluate the prevalence and to document the clinical spectrum of endoscopic reflux esophagitis (RE). STUDY: A total 25,536 subjects underwent an upper gastrointestinal endoscopic examination as part of a health check, and completed a gastroesophageal reflux questionnaire. Endoscopic findings classified according to the Los Angeles (LA) classification and the data from gastroesophageal reflux questionnaire were analyzed. RESULTS: On the basis of endoscopic findings, 2019 subjects (7.91%) were found to have RE: 5.87% in LA-A; 1.84% in LA-B; 0.18% in LA-C; and 0.02% in LA-D. Heartburn, acid regurgitation, chest pain, hoarseness, globus sensation, cough, and epigastric soreness were found to be associated with RE (P<0.05). Heartburn, acid regurgitation, and epigastric soreness were more frequent in LA-B than in LA-A (P<0.05). Epigastric soreness was most bothersome in LA-A and LA-B, and acid regurgitation was most bothersome in LA-C and LA-D (P<0.01). Heartburn, hoarseness, and globus sensation were more frequent in men with RE, and acid regurgitation was most common in women. CONCLUSIONS: The prevalence of RE was found to be 7.91% in Korea, and the profiles of reflux symptoms were found to depend on grade of RE and sex.
Full Text
http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00004836-200908000-00007&LSLINK=80&D=ovft
DOI
10.1097/MCG.0b013e3181855055
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Lee, Yong Chan(이용찬) ORCID logo https://orcid.org/0000-0001-8800-6906
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/105149
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