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Eosinophil-mediated tissue inflammatory responses in helminth infection.

Authors
 Myeong Heon Shin  ;  Young Ah Lee  ;  Duk-Young Min 
Citation
 KOREAN JOURNAL OF PARASITOLOGY, Vol.47(suppl) : 125-131, 2009 
Journal Title
 KOREAN JOURNAL OF PARASITOLOGY 
ISSN
 0023-4001 
Issue Date
2009
MeSH
Animals ; Eosinophils/immunology* ; Eosinophils/parasitology ; Helminthiasis/immunology* ; Helminthiasis/parasitology* ; Helminths/immunology* ; Host-Parasite Interactions ; Humans
Keywords
Eosinophils ; Helminth infection ; Host-parasite interaction ; Tissue inflammation
Abstract
Eosinophilic leukocytes function in host protection against parasitic worms. In turn, helminthic parasites harbor specific molecules to evade or paralyze eosinophil-associated host immune responses; these molecules facilitate the migration and survival of parasitic helminths in vivo. This competition between eosinophil and worm leads to stable equilibria between them. An understanding of such dynamic host-eosinophil interactions will help us to uncover mechanisms of cross talk between host and parasite in helminth infection. In this review, we examine recent findings regarding the innate immune responses of eosinophils to helminthic parasites, and discuss the implications of these findings in terms of eosinophil-mediated tissue inflammation in helminth infection.
Files in This Item:
T200903448.pdf Download
DOI
10.3347/kjp.2009.47.S.S125
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Environmental Medical Biology (환경의생물학교실) > 1. Journal Papers
Yonsei Authors
Shin, Myeong Heon(신명헌) ORCID logo https://orcid.org/0000-0001-8207-6110
Lee, Young Ah(이영아) ORCID logo https://orcid.org/0000-0002-0414-842X
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/105030
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