Cited 10 times in
Potential benefit of intraocular pressure reduction in normal-tension glaucoma in South Korea
DC Field | Value | Language |
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dc.contributor.author | 성공제 | - |
dc.date.accessioned | 2015-04-24T17:14:38Z | - |
dc.date.available | 2015-04-24T17:14:38Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 1080-7683 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/105026 | - |
dc.description.abstract | PURPOSE: The aim of this study was to evaluate the potential benefit of intraocular pressure (IOP) reduction in normal tension glaucoma (NTG) Asian adult patients in South Korea. METHODS: This was a retrospective, multicenter analysis of 166 NTG Asian adult patients in South Korea. The patient population consisted of Korean patients with NTG with at least 5 years of records available for evaluation. Patients all had typical glaucomatous optic-disc and/or visual-field changes but had never had a recorded IOP >21 mmHg. RESULTS: Overall, 48 (29%) patients were progressed and 116 (71%) were stable over the follow-up period. Of patients with IOPs <or=14 mmHg (21/93), 23% progressed and >or=15 mmHg (27/73) 37% progressed (P = 0.041). The mean IOP for the stable group was 14.0 +/- 1.8 mmHg, whereas with the progressed group the average mean IOP was 14.4 +/- 1.6 mmHg (P = 0.20). The mean peak IOP was 17.4 +/- 2.2 mmHg in the stable group and 17.8 +/- 2.0 mmHg in the progressed group (P = 0.26). Multivariate linear regression analysis did not any identify independent risk factors for progression, including age, gender, or mean and peak IOP. CONCLUSIONS: This study provides initial evidence that Korean patients with normal-tension glaucoma, treated to lower IOPs, may have a decreased incidence of progression over 5 years than those patients with higher IOPs. More research is required to confirm this finding | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 91~96 | - |
dc.relation.isPartOf | JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Antihypertensive Agents/therapeutic use* | - |
dc.subject.MESH | Asian Continental Ancestry Group | - |
dc.subject.MESH | Disease Progression | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Glaucoma, Open-Angle/drug therapy* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Intraocular Pressure/drug effects* | - |
dc.subject.MESH | Korea/epidemiology | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Optic Disk/pathology | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Visual Fields | - |
dc.title | Potential benefit of intraocular pressure reduction in normal-tension glaucoma in South Korea | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Ophthalmology (안과학) | - |
dc.contributor.googleauthor | Gong Je Seong | - |
dc.contributor.googleauthor | Sae Heun Rho | - |
dc.contributor.googleauthor | Chang Sik Kim | - |
dc.contributor.googleauthor | Jong Il Moon | - |
dc.contributor.googleauthor | Michael Scott Kook | - |
dc.contributor.googleauthor | Yong Yeon Kim | - |
dc.contributor.googleauthor | Kyoung Tak Ma | - |
dc.contributor.googleauthor | Young Jae Hong | - |
dc.contributor.googleauthor | Lindsay A. Nelson | - |
dc.contributor.googleauthor | Bonnie Kruft | - |
dc.contributor.googleauthor | Jeanette A. Stewart | - |
dc.contributor.googleauthor | William C. Stewart | - |
dc.identifier.doi | 10.1089/jop.2008.0056 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01946 | - |
dc.relation.journalcode | J01654 | - |
dc.identifier.eissn | 1557-7732 | - |
dc.identifier.pmid | 19232005 | - |
dc.identifier.url | http://online.liebertpub.com/doi/abs/10.1089/jop.2008.0056 | - |
dc.contributor.alternativeName | Seong, Gong Je | - |
dc.contributor.affiliatedAuthor | Seong, Gong Je | - |
dc.citation.volume | 25 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 91 | - |
dc.citation.endPage | 96 | - |
dc.identifier.bibliographicCitation | JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, Vol.25(1) : 91-96, 2009 | - |
dc.identifier.rimsid | 56239 | - |
dc.type.rims | ART | - |
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