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베체트병이 합병된 임신에서 산모와 태아의 예후

Other Titles
 The outcome of pregnancy complicated by Behcet`s disease 
 Sue Min Chung  ;  Han Sung Hwang  ;  Yong Won Park  ;  Young Han Kim 
 Korean Journal of Obstetrics and Gynecology (대한산부인과학회지), Vol.52(3) : 309-313, 2009 
Journal Title
Korean Journal of Obstetrics and Gynecology(대한산부인과학회지)
Issue Date
Behçet’s disease ; Pregnancy outcome
Objective: The aim of this study is to investigate the effects of Behcet`s disease (BD) on pregnancy outcome. Methods: We evaluated pregnancies in women who had been diagnosed as BD prior to pregnancy. The medical records of 39 pregnancies in 27 women from May, 1991 to July, 2007 with underlying BD and 499 randomly selected normal pregnancies not associated with BD were retrospectively reviewed. Women with other connective tissue disorders like systemic lupus erythematosus or rheumatoid arthritis and medical illnesses such as diabetes mellitus or hypertension were excluded from the study. The statistical significance was defined as P<0.05. Results: The influence of BD on pregnancy and its outcome were studied in comparison with the normal group. The age, parity, spontaneous abortion rates, delivery weeks, cesarean section rates, premature rupture of membranes, preterm birth, fetal birth weights, APGAR scores, and intrauterine fetal death were compared. Majority of the women with BD were primiparae (P<0.001), and intrauterine fetal death rates (P<0.001) were significantly higher in the study group. The 1-minute APGAR score (P<0.005) of 4 or less and 5-minute APGAR score (P<0.039) of 7 or less appeared more in Behcet`s group. The incidences of pregnancy complications including spontaneous abortion, premature rupture of membranes, preterm birth, and small for gestational age did not show statistically significant differences between the two groups. Conclusion: The results show higher rates of primiparity, lower APGAR scores, and higher intrauterine fetal death rates in patients with BD which implies that the disease may adversely affect pregnancy. Therefore, it is important for pregnant women with BD to receive proper antenatal care and preconception counseling prior to pregnancy.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Young Han(김영한) ORCID logo https://orcid.org/0000-0003-0645-6028
Park, Yong Won(박용원)
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