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Macroscopic Borrmann type as a simple prognostic indicator in patients with advanced gastric cancer

 Chen Li  ;  Sung Jin Oh  ;  Sungsoo Kim  ;  Woo Jin Hyung  ;  Min Yan  ;  Zheng Gang Zhu  ;  Sung Hoon Noh 
 ONCOLOGY, Vol.77(3-4) : 197-204, 2009 
Journal Title
Issue Date
Adult ; Aged ; Female ; Humans ; Lymphatic Metastasis ; Male ; Middle Aged ; Multivariate Analysis ; Prognosis ; Stomach Neoplasms/mortality ; Stomach Neoplasms/pathology* ; Survival Rate
Advanced gastric cancer ; Borrmann type ; Prognosis
BACKGROUND: The purpose of this study was to clarify the clinical significance of macroscopic Borrmann type in advanced gastric cancer. METHODS: From 1987 to 2001, we retrospectively studied the clinicopathological features and prognoses of 3,966 patients with advanced gastric cancer according to the macroscopic classification of Borrmann type. RESULTS: Multivariate analysis showed that gender, Borrmann type and depth of invasion were all associated with the status of nodal involvement. There were statistically significant differences in overall survival among patients with Borrmann type I and II tumors, Borrmann type III tumors, and Borrmann type IV tumors according to depth of invasion (pT) and nodal involvement (pN), except in pN3 tumors. Borrmann type was an independent prognostic factor in patients with advanced gastric cancer. Furthermore, the 5-year survival rates of patients with Borrmann type III and type IV tumors after curative resection were 62.0 and 51.2%, respectively; this was significantly higher than after noncurative resection (17.8 and 18.0%, respectively). CONCLUSION: Macroscopic Borrmann type is a simple and valuable predictor for lymph node metastasis and survival in advanced gastric cancer patients.
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1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Sung Soo(김성수)
Noh, Sung Hoon(노성훈) ORCID logo https://orcid.org/0000-0003-4386-6886
Oh, Sung Jin(오성진)
Hyung, Woo Jin(형우진) ORCID logo https://orcid.org/0000-0002-8593-9214
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