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Amorphous Calcium Polyphosphate Bone Regenerative Materials Based on Calcium Phosphate Glass

DC Field Value Language
dc.contributor.author김민철-
dc.contributor.author이병현-
dc.contributor.author이용근-
dc.contributor.author최성호-
dc.date.accessioned2015-04-24T16:59:16Z-
dc.date.available2015-04-24T16:59:16Z-
dc.date.issued2009-
dc.identifier.issn1013-9826-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/104547-
dc.description.abstractWe developed new calcium phosphate bone substitute material, amorphous calcium polyphosphate. The new material is synthesized by a cement-like slif-setting reaction with calcium phosphate glass, basic materials and water. In this study, we prepared with CPG, Na2CO3 and NaOH solution. When they are mixed together, amorphous phase was precipitated. The precipitated amorphous phase consisted of polyphosphate chains condensed with Na ions released from Na2CO3 and NaOH. When the amorphous calcium polyphosphate dissolves, inorganic polyphosphates are released into the medium. The inorganic polyphosphates as the dissolution product inducted the calcification of the osteoblast cells. Therefore, in animal test, the new bone formation in rat calvarial defects treated with the new material was significantly higher than sham-surgery control group, especially in the initial stage. The amorphous calcium polyphosphate was biocompatible and bioresorbable and promoted the new bone formation-
dc.description.statementOfResponsibilityopen-
dc.format.extent209~212-
dc.relation.isPartOfKey Engineering Materials-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleAmorphous Calcium Polyphosphate Bone Regenerative Materials Based on Calcium Phosphate Glass-
dc.typeArticle-
dc.contributor.collegeCollege of Dentistry (치과대학)-
dc.contributor.departmentDept. of Periodontology (치주과학)-
dc.contributor.googleauthorByung Hyun Lee-
dc.contributor.googleauthorMin Chul Kim-
dc.contributor.googleauthorSeong Ho Choi-
dc.contributor.googleauthorYong Keun Lee-
dc.identifier.doi10.4028/www.scientific.net/KEM.396-398.209-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02799-
dc.contributor.localIdA02976-
dc.contributor.localIdA00478-
dc.contributor.localIdA04081-
dc.relation.journalcodeJ01939-
dc.identifier.urlhttp://www.scientific.net/KEM.396-398.209-
dc.subject.keywordAmorphous calcium polyphosphate-
dc.subject.keywordCalcium phosphate glass-
dc.subject.keywordNon-crystalline material-
dc.subject.keywordBone regenerative material-
dc.contributor.alternativeNameKim, Min Chul-
dc.contributor.alternativeNameLee, Byung Hyun-
dc.contributor.alternativeNameLee, Yong Keun-
dc.contributor.alternativeNameChoi, Seong Ho-
dc.contributor.affiliatedAuthorLee, Byung Hyun-
dc.contributor.affiliatedAuthorLee, Yong Keun-
dc.contributor.affiliatedAuthorKim, Min Chul-
dc.contributor.affiliatedAuthorChoi, Seong Ho-
dc.citation.volume396~398-
dc.citation.startPage209-
dc.citation.endPage212-
dc.identifier.bibliographicCitationKey Engineering Materials, Vol.396~398 : 209-212, 2009-
dc.identifier.rimsid51105-
dc.type.rimsART-
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Dental Biomaterials and Bioengineering (치과생체재료공학교실) > 1. Journal Papers
2. College of Dentistry (치과대학) > Dept. of Periodontics (치주과학교실) > 1. Journal Papers

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