Cited 10 times in
Association of a 5-HT1Dbeta receptor gene polymorphism with obsessive-compulsive disorder in Korean male subjects.
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 강지인 | - |
dc.contributor.author | 김세주 | - |
dc.contributor.author | 김찬형 | - |
dc.contributor.author | 남궁기 | - |
dc.date.accessioned | 2015-04-24T16:56:50Z | - |
dc.date.available | 2015-04-24T16:56:50Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 0302-282X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/104470 | - |
dc.description.abstract | The 5-HT1Dbeta receptor gene appears to be particularly interesting in the pathophysiology of obsessive-compulsive disorder (OCD). The 5-HT1Dbeta receptor is a terminal autoreceptor involved in the regulation of serotonin synthesis and release. We performed an association study of the G861C single nucleotide polymorphism (SNP) of the 5-HT1Dbeta receptor in 167 male Korean OCD subjects and in 107 controls. Individuals with the G allele had an increased chance of having OCD (OR 1.49, 95% CI 1.05-2.10). Our findings suggest an association between the G861C SNP of the 5-HT1Dbeta receptor and males with OCD. In the future, other tag SNPs that cover the entire 5-HT1Dbeta gene region as well as additional SNPs that are supposed to have meaningful functions should be investigated in both male and female OCD subjects | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 96~99 | - |
dc.relation.isPartOf | NEUROPSYCHOBIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Alleles | - |
dc.subject.MESH | Case-Control Studies | - |
dc.subject.MESH | Genome-Wide Association Study | - |
dc.subject.MESH | Genotype | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Korea | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Obsessive-Compulsive Disorder/genetics* | - |
dc.subject.MESH | Polymorphism, Single Nucleotide* | - |
dc.subject.MESH | Receptor, Serotonin, 5-HT1B/genetics* | - |
dc.title | Association of a 5-HT1Dbeta receptor gene polymorphism with obsessive-compulsive disorder in Korean male subjects. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Psychiatry (정신과학) | - |
dc.contributor.googleauthor | Se Joo Kim | - |
dc.contributor.googleauthor | Kee Namkoong | - |
dc.contributor.googleauthor | Jee In Kang | - |
dc.contributor.googleauthor | Chan-Hyung Kim | - |
dc.identifier.doi | 10.1159/000209861 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00084 | - |
dc.contributor.localId | A00604 | - |
dc.contributor.localId | A01036 | - |
dc.contributor.localId | A01240 | - |
dc.relation.journalcode | J02354 | - |
dc.identifier.eissn | 1423-0224 | - |
dc.identifier.pmid | 19325252 | - |
dc.identifier.url | http://www.karger.com/Article/FullText/209861 | - |
dc.subject.keyword | 5-HT1D receptor gene | - |
dc.subject.keyword | Obsessive-compulsive disorder | - |
dc.subject.keyword | Single nucleotide polymorphism | - |
dc.contributor.alternativeName | Kang, Jee In | - |
dc.contributor.alternativeName | Kim, Se Joo | - |
dc.contributor.alternativeName | Kim, Chan Hyung | - |
dc.contributor.alternativeName | Namkoong, Kee | - |
dc.contributor.affiliatedAuthor | Kang, Jee In | - |
dc.contributor.affiliatedAuthor | Kim, Se Joo | - |
dc.contributor.affiliatedAuthor | Kim, Chan Hyung | - |
dc.contributor.affiliatedAuthor | Namkoong, Kee | - |
dc.citation.volume | 59 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 96 | - |
dc.citation.endPage | 99 | - |
dc.identifier.bibliographicCitation | NEUROPSYCHOBIOLOGY, Vol.59(2) : 96-99, 2009 | - |
dc.identifier.rimsid | 54144 | - |
dc.type.rims | ART | - |
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