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최근 임상검체에서의 혐기성 세균 분리 현황 및 혐기성 균혈증의 임상적 특징

DC FieldValueLanguage
dc.contributor.author김준명-
dc.contributor.author박용정-
dc.contributor.author용동은-
dc.contributor.author이경원-
dc.contributor.author이양순-
dc.contributor.author정석훈-
dc.contributor.author정윤섭-
dc.contributor.author최준용-
dc.date.accessioned2015-04-24T16:55:03Z-
dc.date.available2015-04-24T16:55:03Z-
dc.date.issued2009-
dc.identifier.issn1598-8112-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/104415-
dc.description.abstractBACKGROUND: Anaerobic bacteria can cause various infections, and their incidence may differ greatly, depending on the country or hospital. We investigated recent trends in anaerobe isolation and clinical characteristics of anaerobic bacteremia in one hospital in Korea to facilitate diagnosis and treatment of anaerobic infections. MATERIALS AND METHODS: Anaerobic bacteria isolated from blood, body fluids and abscess specimens at a university hospital in Korea during 2007 and 2008 were analyzed. The medical records of 82 anaerobic bacteremia patients were reviewed. A retrospective cohort study was conducted to determine the risk factors for in-hospital mortality of patients with anaerobic bacteremia. RESULTS: A total of 289 non-duplicated anaerobic isolates were recovered from blood, body fluids and abscess specimens. Bacteroides fragilis (73 isolates, 25.3%) was the most common organism followed by Clostridium perfringens (22 isolates, 7.6%), Peptoniphilus asaccharolyticus (21 isolates, 7.3%) and Anaerococcus prevotii (19 isolates, 6.6%). Eighty-four isolates were recovered from blood specimens, among which B. fragilis (24 isolates) and C. perfringens (21 isolates) were the most frequently isolated organisms. Among the 196 underlying diseases of anaerobic bacteremia patients, neoplastic, infectious, and gastrointestinal diseases accounted for 54 (27.6%), 46 (23.5%), and 41 (20.9%) cases, respectively. The alimentary tract was the most common suspected portal of entry. The in-hospital mortality rate of anaerobic bacteremia patients was 34.2%, and neutropenia at the time of blood culture was the only statistically significant factor associated with mortality in this study. Anaerobes were isolated in 1.4% of all positive blood cultures. CONCLUSIONS: B. fragilis and C. perfringens are expected to be commonly isolated from clinical specimens. Despite its low prevalence, anaerobic bacteremia displays a significant in-hospital mortality rate. Ongoing investigations into anaerobic bacteremia are necessary because of ambiguous risk factors for mortality-
dc.description.statementOfResponsibilityopen-
dc.format.extent216~223-
dc.relation.isPartOfINFECTION AND CHEMOTHERAPY (감염과 화학요법)-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.title최근 임상검체에서의 혐기성 세균 분리 현황 및 혐기성 균혈증의 임상적 특징-
dc.title.alternativeRecent Trends of Anaerobic Bacteria Isolated from Clinical Specimens and Clinical Characteristics of Anaerobic Bacteremia-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthor박용정-
dc.contributor.googleauthor이양순-
dc.contributor.googleauthor김명숙-
dc.contributor.googleauthor최준용-
dc.contributor.googleauthor용동은-
dc.contributor.googleauthor정석훈-
dc.contributor.googleauthor김준명-
dc.contributor.googleauthor이경원-
dc.contributor.googleauthor정윤섭-
dc.identifier.doi10.3947/ic.2009.41.4.216-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00953-
dc.contributor.localIdA01582-
dc.contributor.localIdA02423-
dc.contributor.localIdA02649-
dc.contributor.localIdA02947-
dc.contributor.localIdA03619-
dc.contributor.localIdA03679-
dc.contributor.localIdA04191-
dc.relation.journalcodeJ01054-
dc.subject.keywordAnaerobe-
dc.subject.keywordBacteremia-
dc.subject.keywordBacteroides fragilis-
dc.subject.keywordClostridium perfringens-
dc.contributor.alternativeNameKim, June Myung-
dc.contributor.alternativeNamePark, Yong Jung-
dc.contributor.alternativeNameYong, Dong Eun-
dc.contributor.alternativeNameLee, Kyung Won-
dc.contributor.alternativeNameLee, Yang Soon-
dc.contributor.alternativeNameJeong, Seok Hoon-
dc.contributor.alternativeNameChong, Yun Sop-
dc.contributor.alternativeNameChoi, Jun Yong-
dc.contributor.affiliatedAuthorKim, June Myung-
dc.contributor.affiliatedAuthorPark, Yong Jung-
dc.contributor.affiliatedAuthorYong, Dong Eun-
dc.contributor.affiliatedAuthorLee, Kyung Won-
dc.contributor.affiliatedAuthorLee, Yang Soon-
dc.contributor.affiliatedAuthorJeong, Seok Hoon-
dc.contributor.affiliatedAuthorChong, Yun Sop-
dc.contributor.affiliatedAuthorChoi, Jun Yong-
dc.citation.volume41-
dc.citation.number4-
dc.citation.startPage216-
dc.citation.endPage223-
dc.identifier.bibliographicCitationINFECTION AND CHEMOTHERAPY (감염과 화학요법), Vol.41(4) : 216-223, 2009-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers

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