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A comparison of treatment plans using linac-based intensity-modulated radiation therapy and helical tomotherapy for maxillary sinus carcinoma

Authors
 Songyih Kim  ;  Ik Jae Lee  ;  Yong Bae Kim  ;  Woong Sub Koom  ;  Byeong Chul Jeon  ;  Chang Geol Lee  ;  Gwi Eon Kim  ;  Ki Chang Keum 
Citation
 TECHNOLOGY IN CANCER RESEARCH & TREATMENT, Vol.8(4) : 257-263, 2009 
Journal Title
 TECHNOLOGY IN CANCER RESEARCH & TREATMENT 
ISSN
 1533-0346 
Issue Date
2009
MeSH
Adult ; Aged ; Brain Stem/pathology ; Female ; Humans ; Male ; Maxillary Sinus Neoplasms/pathology ; Maxillary Sinus Neoplasms/radiotherapy* ; Middle Aged ; Radiotherapy Dosage ; Radiotherapy Planning, Computer-Assisted* ; Radiotherapy, Intensity-Modulated/methods* ; Tomography, Spiral Computed/methods* ; Visual Pathways/pathology
Keywords
Maxillary sinus cancer ; Tomotherapy ; Dosimetric comparison
Abstract
This study evaluated whether helical tomotherapy (TOMO) planning could achieve better isodose distribution for the maxillary sinus while concomitantly sparing the adjacent _critical normal organs than linac-based step-and-shoot IMRT (s-IMRT) planning. TOMO and s-IMRT were established for 10 patients with maxillary sinus cancer. The prescription (66 Gy, 30 fractions) was used to cover the planning target volume (PTV) with a 95% isodose line. Each plan was independently optimized using the CORVUS planning system and Tomotherapy Hi-Art system. The treatment plans were compared using dose volume histogram (DVH), a dose homogeneity index (DHI) of the PTV, and equivalent uniform dose (EUD) and DVH of organs at risk (OARs). The TOMO plans demonstrated better dose homogeneity compared to the s-IMRT plans. The average V95% of the TOMO plans was similar to that of the s-IMRT (92.92% vs. 95.07%, respectively), but the average V107% was 0% for TOMO compared with 18.74% for s-IMRT. The average maximum dose reduction was 7 Gy, and DHI increased by 8% for PTV1 in TOMO compared with s-IMRT (79 Gy vs. 71 Gy and, 89% vs. 97%, respectively). The average EUD reduction for the optic nerve was 17%. In summary, planning with TOMO was superior to s-IMRT planning with respect to dose homogeneity within the PTV and sparing of the optic nerve
Full Text
http://www.tcrt.org/c3036/c4291/A-Comparison-of-Treatment-Plans-using-Linac-Based-Intensity-Modulated-Radiation-Therapy-and-Helical-Tomotherapy-for-Maxillary-Sinus-Carcinoma-p-257-264-p17645.html
DOI
10.1177/153303460900800402
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiation Oncology (방사선종양학교실) > 1. Journal Papers
Yonsei Authors
Keum, Ki Chang(금기창) ORCID logo https://orcid.org/0000-0003-4123-7998
Koom, Woong Sub(금웅섭) ORCID logo https://orcid.org/0000-0002-9435-7750
Kim, Gwi Eon(김귀언)
Kim, Yong Bae(김용배) ORCID logo https://orcid.org/0000-0001-7573-6862
Lee, Ik Jae(이익재) ORCID logo https://orcid.org/0000-0001-7165-3373
Lee, Chang Geol(이창걸) ORCID logo https://orcid.org/0000-0002-8702-881X
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/104290
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