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Efficacy of the fractional photothermolysis system with dynamic operating mode on acne scars and enlarged facial pores.

Authors
 SUNG BIN CHO  ;  JU HEE LEE  ;  MOON JUNG CHOI  ;  KYU-YEOP LEE  ;  SANG HO OH 
Citation
 DERMATOLOGIC SURGERY, Vol.35(1) : 108-114, 2009 
Journal Title
 DERMATOLOGIC SURGERY 
ISSN
 1076-0512 
Issue Date
2009
MeSH
Acne Vulgaris/complications* ; Acne Vulgaris/pathology ; Adult ; Cicatrix/etiology ; Cicatrix/therapy* ; Female ; Humans ; Laser Therapy/instrumentation ; Laser Therapy/methods* ; Male ; Phototherapy/instrumentation ; Phototherapy/methods* ; Skin/pathology*
Abstract
BACKGROUND: Current treatments for acne scars and enlarged facial pores have shown limited efficacy. OBJECTIVE: To evaluate the efficacy and safety of the fractional photothermolysis system (FPS) with dynamic operating mode on acne scars and enlarged pores. MATERIALS AND METHODS: Twelve patients with mild to moderate atrophic acne scars and enlarged pores were included in this study. Three sessions of FPS treatment were performed for acne scars and facial pores monthly. Two blinded dermatologists who compared before and after photos based on a quartile grading scale conducted objective clinical assessments of acne scar- and facial pore-treated areas. We took a biopsy immediately after one treatment with the laser from one of the authors to assess the histologic effects of the laser on facial pores. RESULTS: Follow-up results at 4 months after the last treatment revealed that, of the 12 patients, for acne scars, five demonstrated clinical improvements of 51% to 75% and three demonstrated improvements of 76% to 100%, and for facial pores, five demonstrated moderate clinical improvements of 26% to 50% and three demonstrated improvements of 76% to 100%. Side effects, including pain, post-treatment erythema, and edema, were resolved within 1 week. CONCLUSION: We suggest that the FPS may provide a new treatment algorithm in some cases with acne scars and enlarged pores. Considering the lack of placebo-controlled, split-face design of our study, optimized, prospective studies should be conducted to fully assess the efficacy of FPS with dynamic operating mode.
Full Text
http://onlinelibrary.wiley.com/doi/10.1111/j.1524-4725.2008.34399.x/abstract
DOI
10.1111/j.1524-4725.2008.34399.x
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers
Yonsei Authors
Oh, Sang Ho(오상호) ORCID logo https://orcid.org/0000-0002-4477-1400
Lee, Ju Hee(이주희) ORCID logo https://orcid.org/0000-0002-1739-5956
Cho, Sung Bin(조성빈)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/103990
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