악성 섬유성 및 섬유조직구성 종양에 대한 임상적 고찰 -대한피부과학회 피부암 연구분과위원회 공동연구-

Abstract

Background: Malignant fibrous/fibrohistiocytic tumors are uncommon soft tissue tumors which gives dermatologists special attention on differential diagnosis. However, there has not yet been a multicenter study on these tumors in Korea. Objective: The aim of this study was to investigate the epidemiology and clinical features of malignant fibrous/fiborhistiocytic tumors. Methods: A total of 62 patients from 11 training hospitals who had been confirmed with malignant fibrous/fibrohistiocytic tumor were studied. A retrospective analysis of hospital records served as the data source for this study. Results: Among patients with malignant fibrous/fibrohistiocytic tumors, the most common tumor type was dermatofibrosarcoma protuberance followed by malignant fibrohistiocytic. The male to female ratio among subjects was 1.38 to 1 and the mean age was 44 years old. Of the common complaints recorded, asymptomatic mass was the most frequent. The mean size of the subjects` tumors was 2.9 cm in the long axis and 2.3 cm in the short axis with a mean tumor thickness of 2.1 mm. The most common site for tumors was the back followed by the thigh. The recurrence rate after primary treatment was 14.5% and metastasis developed in 5 of 62 patients. Conclusion: This study is expected to be helpful for understanding the clinical and pathological characteristics of malignant fibrous/fibrohistiocytic tumors.