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Long-term follow up of gallbladder polyps

Authors
 Jeong Youp Park  ;  Sung Pil Hong  ;  Yoon Jae Kim  ;  Hong Jeoung Kim  ;  Hee Man Kim  ;  Jae Hee Cho  ;  Seung Woo Park  ;  Si Young Song  ;  Jae Bock Chung  ;  Seungmin Bang 
Citation
 JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, Vol.24(2) : 219-222, 2009 
Journal Title
 JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY 
ISSN
 0815-9319 
Issue Date
2009
MeSH
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Cell Transformation, Neoplastic/pathology* ; Cholecystectomy ; Early Detection of Cancer ; Female ; Follow-Up Studies ; Gallbladder Diseases/diagnostic imaging ; Gallbladder Diseases/pathology* ; Gallbladder Diseases/surgery ; Gallbladder Neoplasms/diagnostic imaging ; Gallbladder Neoplasms/pathology* ; Gallbladder Neoplasms/surgery ; Gallstones/pathology ; Humans ; Male ; Middle Aged ; Polyps/diagnostic imaging ; Polyps/pathology* ; Polyps/surgery ; Precancerous Conditions/diagnostic imaging ; Precancerous Conditions/pathology* ; Precancerous Conditions/surgery ; Predictive Value of Tests ; Risk Assessment ; Risk Factors ; Time Factors ; Ultrasonography ; Young Adult
Keywords
gallbladder ; gallbladder cancer ; gallbladderpolyp ; ultrasonography
Abstract
BACKGROUND AND AIM: The management of gallbladder polyps (GBP) is directly linked to the early diagnosis of gallbladder cancer (GBC). This study aimed to evaluate the malignant risk of GBP. METHODS: In total, 1558 patients diagnosed with GBP were followed. Neoplastic polyps were defined as GBC and its premalignant lesions. The risk for malignancy was estimated with the cumulative detection rate of neoplastic polyps. RESULTS: Thirty-three cases (2.1%) were diagnosed with neoplastic polyps. The cumulative detection rates of neoplastic polyps were 1.7% at 1 year, 2.8% at 5 years, and 4% at 8 years after diagnosis. The size of GBP and the presence of gallstones were risk factors for neoplastic polyps. Polyps > or = 10 mm had a 24.2 times greater risk of malignancy than polyps < 10 mm. However, 15 of 33 neoplastic polyps (45.5%) were < 10 mm at the time of diagnosis of GBP. During follow up in 36 (3.5%) of 1027 cases, an increase in size was detected; of these, nine (25%) had neoplastic polyps. CONCLUSION: Even small polyps have a risk of malignancy, and careful long-term follow up of GBP will help detect and treat early GBC.
Full Text
http://onlinelibrary.wiley.com/doi/10.1111/j.1440-1746.2008.05689.x/abstract
DOI
10.1111/j.1440-1746.2008.05689.x
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Yoon Jae(김윤재)
Kim, Hong Jeoung(김홍정)
Kim, Hee Man(김희만)
Park, Seung Woo(박승우) ORCID logo https://orcid.org/0000-0001-8230-964X
Park, Jeong Youp(박정엽) ORCID logo https://orcid.org/0000-0003-0110-8606
Bang, Seungmin(방승민) ORCID logo https://orcid.org/0000-0001-5209-8351
Song, Si Young(송시영) ORCID logo https://orcid.org/0000-0002-1417-4314
Chung, Jae Bock(정재복)
Cho, Jae Hee(조재희)
Hong, Sung Pil(홍성필)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/103452
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