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베체트병에서 뼈신티그래피를 통한 관절 침범의 평가

 한은천  ;  오상호  ;  방동식 
 Korean Journal of Dermatology (대한피부과학회지), Vol.47(1) : 30-35, 2009 
Journal Title
Korean Journal of Dermatology(대한피부과학회지)
Issue Date
Articular involvement ; Behçet's disease ; Bone scintigraphy
Background: Behcet`s disease (BD) is a chronic relapsing inflammatory disease that involves various organ systems. Articular involvement was reported to be present in approximately 50% of Korean BD patients. The joint symptoms of BD patients have usually been described as intermittent, self-limiting and non-erosive, and they are mostly monoarticular and oligoarticular arthritis. Objective: The purpose of our investigations was to evaluate the usefulness of bone scintigraphy for detecting the articular involvement of BD. Methods: We reviewed the medical records, laboratory findings and bone scintigraphy findings of 89 patients who were diagnosed with BD from January 2005 to June 2007. Results: Of the 89 BD patients, 14 patients were male and 75 patients were female with a mean age of 43.92±8.49 yr. The most frequently involved site on bone scintigraphy was the wrist (44.9%) with the decreasing order of frequency as follows: the feet (39.3%), the hands (25.8%), the knee (24.7%), the sacroiliac joint (22.4%), the shoulder (18%), the ankle (16.9%), the hip (12.6%), the spine (10%) and the elbow (3%). The pattern of involvement, which was defined as the number of joints showing hot uptake on the bone scintigraphy at one episode of arthropathy, was monoarticular in 5.6%, oligoarticular in 44.9%, polyarticular in 38.2% and there was no uptake in 11.2%. Among 130 joints, 63.1% of the joints showed close correlation between the clinical symptoms and the bone scintigraphy uptake. Conclusion: We suggest that bone scintigraphy can be a useful tool to determine the presence and site of articular involvement. However, more studies are needed to exclude non-specific bone scintigraphy uptake and to determine the correlation between clinical symptoms and the bone scintigraphy findings.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers
Yonsei Authors
Bang, Dong Sik(방동식)
Oh, Sang Ho(오상호) ORCID logo https://orcid.org/0000-0002-4477-1400
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