뇌혈관질환의 항혈전제 치료에 있어서 약물유전학

Abstract

Pharmacogenetics is an emerging field to find out genetic variations that explains different individual responses to given drug. Pharmacogenetics may be the basis of tailored medicine because it can help to predict drug resistance, side effect and dose adjustment. This review discusses current role of pharmacogenetics in antithrombotic treatment in cerebrovascular disease, especially focused on vitamin K antagonist and clopidogrel