111 272

Cited 0 times in

Antibiotic Microbial Prophylaxis for Spinal Surgery: Comparison between 48 and 72-Hour AMP Protocols

Authors
 Boram Kim  ;  Seong-Hwan Moon  ;  Eun-Su Moon  ;  Hak-Sun Kim  ;  Jin-Oh Park  ;  In-Je Cho  ;  Hwan-Mo Lee 
Citation
 ASIAN SPINE JOURNAL, Vol.4(2) : 71-76, 2010 
Journal Title
 ASIAN SPINE JOURNAL 
ISSN
 1976-1902 
Issue Date
2010
Keywords
Anti-bacterial agents ; Spine ; Surgical site infection
Abstract
STUDY DESIGN: This is a prospective randomized cohort study. PURPOSE: We intended to evaluate the efficacy of a 48 hour antibiotic microbial prophylaxis (AMP) protocol as compared with a 72 hour AMP protocol. OVERVIEW OF LITERATURE: The current guideline for the prevention of surgical site infection (SSI) suggests the AMP should not exceed 24 hours after clean surgery like spinal surgery. But there exist some confusion in real clinical practice about the duration of postoperative antibiotic administration because the evidence of the guideline was not robust. METHODS: The subjects were 548 patients who underwent spinal surgery at our department from April 2007 to December 2008. The patients were classified into two groups according to the prophylaxis protocol: group A, for which AMP was employed for 72 hours postoperatively and group B, for which AMP was employed for 48 hours postoperatively. Five hundred two patients out of 548 patients were followed until 6 months postoperatively. The incidence of SSI in the two groups was analyzed. RESULTS: The overall infection rate was 0.8%. There was no significant difference in infection rate between the two groups. The overall infection rate for the patients who underwent instrumented fusion was 0.9%. There was no significant difference in the infection rate between the patients of the two groups who underwent instrumented fusion. CONCLUSIONS: AMP for 48 hours is as efficient as AMP for 72 hours.
Files in This Item:
T201004125.pdf Download
DOI
10.4184/asj.2010.4.2.71
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Orthopedic Surgery (정형외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Bo Ram(김보람)
Kim, Hak Sun(김학선) ORCID logo https://orcid.org/0000-0002-8330-4688
Moon, Seong Hwan(문성환)
Moon, Eun Su(문은수)
Park, Jin Oh(박진오)
Lee, Hwan Mo(이환모) ORCID logo https://orcid.org/0000-0002-5405-3832
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/102636
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse