Cited 25 times in
Efficacy of antiadhesion barrier solution on periimplant capsule formation in a white rat model
DC Field | Value | Language |
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dc.contributor.author | 유대현 | - |
dc.contributor.author | 탁관철 | - |
dc.contributor.author | 홍종원 | - |
dc.date.accessioned | 2015-04-23T17:29:28Z | - |
dc.date.available | 2015-04-23T17:29:28Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 0148-7043 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/102565 | - |
dc.description.abstract | Antiadhesive barrier solution (AABS) has been proven to prevent intraabdominal adhesion by reducing inflammation and fibrosis formation. Because this mechanism can also be applied to capsule formation after the breast implant insertion, we hypothesize that AABS can reduce capsular contraction and evaluate the efficacy of AABS on perisilastic implant capsule formation after submuscular insertion. A silicone block was inserted beneath the panniculus carnosus muscle in 10 rats. The experiment group received 0.1 mL of AABS (Guardix, Hanmi Medical Co.) instilled into the pocket, whereas the control group received 0.1 mL saline solution. Periimplant capsules were excised after 4 weeks and were evaluated for inflammatory cell count, capsular thickness, collagen pattern, and amount of myofibroblast. The inflammatory cell count and the capsular thickness were lower in the experiment group than in the control group (P < 0.05). The collagen pattern was loose and parallel in the experiment group, and the amount of myofibroblast was much less compared with the control group. AABS reduced the amount of inflammatory cells, myofibroblast, and capsular thickness. It also made the collagen fibers in the capsule loose and parallel. Therefore, AABS seemed to be effective in reducing the periimplant capsule formation. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 254~258 | - |
dc.relation.isPartOf | ANNALS OF PLASTIC SURGERY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Animals | - |
dc.subject.MESH | Breast Implantation/adverse effects* | - |
dc.subject.MESH | Carboxymethylcellulose Sodium/pharmacology* | - |
dc.subject.MESH | Cell Count | - |
dc.subject.MESH | Contracture/prevention & control | - |
dc.subject.MESH | Disease Models, Animal | - |
dc.subject.MESH | Drug Combinations | - |
dc.subject.MESH | Hyaluronic Acid/pharmacology* | - |
dc.subject.MESH | Immunohistochemistry | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Rats | - |
dc.subject.MESH | Rats, Sprague-Dawley | - |
dc.subject.MESH | Silicones | - |
dc.subject.MESH | Tissue Adhesions/pathology | - |
dc.subject.MESH | Tissue Adhesions/prevention & control* | - |
dc.title | Efficacy of antiadhesion barrier solution on periimplant capsule formation in a white rat model | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Plastic Surgery & Reconstructive Surgery (성형외과학) | - |
dc.contributor.googleauthor | Dae Hyun Lew | - |
dc.contributor.googleauthor | Jung Ho Yoon | - |
dc.contributor.googleauthor | Jong Won Hong | - |
dc.contributor.googleauthor | Kwan Chul Tark | - |
dc.identifier.doi | 10.1097/SAP.0b013e3181c60f1f | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02459 | - |
dc.contributor.localId | A04236 | - |
dc.contributor.localId | A04436 | - |
dc.relation.journalcode | J00176 | - |
dc.identifier.eissn | 1536-3708 | - |
dc.identifier.pmid | 20606576 | - |
dc.identifier.url | http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00000637-201008000-00030&LSLINK=80&D=ovft | - |
dc.contributor.alternativeName | Lew, Dae Hyun | - |
dc.contributor.alternativeName | Tark, Kwan Chul | - |
dc.contributor.alternativeName | Hong, Jong Won | - |
dc.contributor.affiliatedAuthor | Lew, Dae Hyun | - |
dc.contributor.affiliatedAuthor | Tark, Kwan Chul | - |
dc.contributor.affiliatedAuthor | Hong, Jong Won | - |
dc.citation.volume | 65 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 254 | - |
dc.citation.endPage | 258 | - |
dc.identifier.bibliographicCitation | ANNALS OF PLASTIC SURGERY, Vol.65(2) : 254-258, 2010 | - |
dc.identifier.rimsid | 49836 | - |
dc.type.rims | ART | - |
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