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Obesity paradox in Korean patients undergoing primary percutaneous coronary intervention in ST-segment elevation myocardial infarction

Authors
 Won Yu Kang  ;  Myung Ho Jeong  ;  Young Keun Ahn  ;  Jong Hyun Kim  ;  Shung Chull Chae  ;  Young Jo Kim  ;  Seung Ho Hur  ;  In Whan Seong  ;  Taek Jong Hong  ;  Dong Hoon Choi  ;  Myeong Chan Cho  ;  Chong Jin Kim  ;  Ki Bae Seung  ;  Wook Sung Chung  ;  Yang Soo Jang  ;  Seung Woon Rha  ;  Jang Ho Bae  ;  Jeong Gwan Cho  ;  Seung Jung Park 
Citation
 JOURNAL OF CARDIOLOGY, Vol.55(1) : 84-91, 2010 
Journal Title
 JOURNAL OF CARDIOLOGY 
ISSN
 0914-5087 
Issue Date
2010
MeSH
Aged ; Angioplasty, Balloon* ; Body Mass Index ; Coronary Angiography ; Electrocardiography ; Female ; Humans ; Korea ; Male ; Myocardial Infarction/mortality ; Myocardial Infarction/physiopathology* ; Myocardial Infarction/therapy* ; Obesity/complications* ; Treatment Outcome
Keywords
Acute myocardial infarction ; Coronary artery disease ; Obesity ; Prognosis
Abstract
The effect of body mass index (BMI) on outcomes after primary percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI) is not well known. In patients registered in the Korean Acute Myocardial Infarction Registry (KAMIR) between November 2005 and November 2007, 3824 STEMI patients who arrived at hospital within 12h after onset of chest pain and underwent primary PCI were analyzed, and divided into four groups according to their BMI: underweight (BMI<18.5 kg/m(2), n=129); normal weight (18.5 < or =BMI <23.0 kg/m(2), n=1253); overweight (23.0 < or =BMI <27.5 kg/m(2), n=1959); and obese (BMI > or =27.5 kg/m(2), n=483). In-hospital mortality, revascularization in 1 year, mortality in 1 year, and overall mortality were compared between groups. Overweight and obese group were significantly younger, had normal left ventricular ejection fraction, and were more likely to be men with a higher incidence of hypertension, diabetes, and hyperlipidemia. There were no significant differences in symptom-to-door time and door-to-balloon time between groups. Obese patients had significantly lower in-hospital and overall mortalities. Major adverse cardiac events showed a bimodal pattern. Obese STEMI patients treated with primary PCI were associated with lower mortality, which may be explained by better use of medical treatment, hemodynamic stability, and younger age
Full Text
http://www.sciencedirect.com/science/article/pii/S0914508709002780
DOI
10.1016/j.jjcc.2009.10.004
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Jang, Yang Soo(장양수) ORCID logo https://orcid.org/0000-0002-2169-3112
Choi, Dong Hoon(최동훈) ORCID logo https://orcid.org/0000-0002-2009-9760
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/102467
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