242 162

Cited 15 times in

Periodic variation and its effect on management and prognosis of Korean patients with acute myocardial infarction

 Hyo Eun Park  ;  Bon-Kwon Koo  ;  Wonjae Lee  ;  Youngjin Cho  ;  Jin Sik Park  ;  Ji-Yong Choi  ;  Myung-Ho Jeong  ;  Jong Hyun Kim  ;  Shung Chull Chae  ;  Young Jo Kim  ;  Chang-Wook Nam  ;  Jae-Hwan Lee  ;  Dong Hoon Choi  ;  Taek Jong Hong  ;  Jei Keon Chae  ;  Jae Young Rhew  ;  Kee Sik Kim  ;  Hyo-Soo Kim  ;  Byung-Hee Oh  ;  Young Bae Park 
 CIRCULATION JOURNAL, Vol.74(5) : 970-976, 2010 
Journal Title
Issue Date
Aged ; Asian Continental Ancestry Group ; Circadian Rhythm* ; Female ; Hospital Mortality ; Humans ; Incidence ; Male ; Middle Aged ; Myocardial Infarction/mortality* ; Myocardial Infarction/therapy ; Prospective Studies ; Registries* ; Republic of Korea/epidemiology ; Seasons* ; Time Factors
Acute myocardial infarction ; Circadian variation ; Periodic variation
BACKGROUND: The characteristics of the periodic variation in acute myocardial infarction (AMI) and the subsequent effect on management and prognosis have not been fully investigated in a large number of Asian populations. METHODS AND RESULTS: From a prospective, observational multicenter online registry, 4,573 patients diagnosed as AMI in Korea from January to December 2006 were included. The highest incidence of AMI was between 8 a.m. and noon. The number of cases was highest in the winter and lowest in the autumn (13.6 vs 11.4 patients per day, P<0.001). Patients with symptom onset during working hours had a shorter time to first medical contact (203+/-288 min) compared with out-of-hours onset (230+/-288 min, P=0.003). In patients who underwent primary angioplasty, out-of hours symptom onset was associated with a greater time delay in both the patient's and the medical facility's response (door-to-balloon time out-of hours vs working hours: 101+/-54 min vs 84+/-44 min, P<0.001). In patients with ST-segment elevation myocardial infarction, symptoms to first medical contact showed a significant relationship to in-hospital mortality (for every 10 min of symptoms to first medical contact, odds ratio 1.006, 95% confidence interval 1.001-1.012, P=0.018) CONCLUSIONS: Circadian and periodic variation in AMI exists in Korean patients, which resulted in different patient behavior, hospital management and outcomes.
Files in This Item:
T201003767.pdf Download
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Choi, Dong Hoon(최동훈) ORCID logo https://orcid.org/0000-0002-2009-9760
사서에게 알리기


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.