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급성 뇌경색 환자에서 경동맥 죽상경화판과 내중막 두께 측정의 유용성

Other Titles
 Usefulness of Carotid Plaque and Intima-Media Thickness Measurement in Patients with Acute Ischemic Stroke 
Authors
 이재정  ;  홍진용  ;  정요한  ;  최정혜  ;  이성익  ;  차명진  ;  김영대  ;  허지회  ;  남효석 
Citation
 Journal of Neurosonology (신경초음파학회지), Vol.2(1) : 19-26, 2010 
Journal Title
 Journal of Neurosonology  (신경초음파학회지) 
ISSN
 2005-7881 
Issue Date
2010
Abstract
Background: Patients with risk factors for atherosclerosis is prone to develop carotid plaque or increased intima-media thickness (IMT). We explored the association of carotid plaque, atherosclerotic risk factors, frequency of large artery atherosclerosis (LAA) stroke mechanism, and IMT in acute ischemic stroke patients. Methods: From November 2005 to March 2008, total 633 acute ischemic stroke patients, who were examined with a carotid sonography, were enrolled. The atherosclerotic risk factors and number of plaque, maximum plaque size, and maximum IMT were compared. Results: Of the 633 patients, 496 (78.3%) had one or more carotid plaques [median 2, interquartile range (IQR) 2-5]. Patients with carotid plaques were older (p<0.001), male predominance (p=0.014), more frequent history of hypertension (p<0.001), diabetes (p<0.001), higher Framingham Stroke Risk Score (14.1±4.5 vs. 10.3±4.6, p<0.001), and increased IMT (0.99±0.16 vs. 0.87±0.24, p<0.001) than patients without carotid plaque. Comparing other subtypes of stroke classification, LAA were more frequently found in higher quartiles of number of plaques (p=0.005), or maximum plaque size (p=0.016) but IMT had no significant difference (p=0.214). Conclusions: Carotid plaques were associated with atherosclerotic risk factors, and LAA of stroke classification. Either carotid plaque distribution (number) or severity (maximal thickness) in carotid sonography might be used as a predictor of atherothrombotic infarction in patients with acute ischemic stroke
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1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Young Dae(김영대) ORCID logo https://orcid.org/0000-0001-5750-2616
Nam, Hyo Suk(남효석) ORCID logo https://orcid.org/0000-0002-4415-3995
Cha, Myoung Jin(차명진)
Heo, Ji Hoe(허지회) ORCID logo https://orcid.org/0000-0001-9898-3321
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/102327
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