의료용 접착제 및 유착방지막의 최신 연구개발 동향

Abstract

In the case of surgical operation for the treatment of cancers, vascular diseases and diabetes mellitus, the use of medical (or biotissue) adhesives is gradually increasing instead of suturing. Together with this trend, the development of anti-adhesion membranes (or barriers) is rapidly increasing for preventing complications originated from post-operative tissue adhesions frequently occurring. In general, all medical devices should pass the testing for biological safety and effectiveness. Thus, newly developed medical adhesives and anti-adhesion membranes must be evaluated according to the well-regulated standard guidelines, such as ISO, OECD, ASTM, etc, under authorized institution, otherwise they cannot be commercialized. In this review, medical adhesives and anti-adhesion membranes were categorized and compared according to their use and materials followed by a brief description of the properties of products commercially available. Furthermore, this review dealt with the present state of commercialization, the size of market and the recent trends of research and development regarding medical adhesives and anti-adhesion membranes. Key words: Medical adhesives, Anti-adhesion membranes, Medical devices, Safety and Effectiveness