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Uterine and umbilical artery Doppler velocimetry as a predictor for adverse pregnancy outcomes in pregnant women with anemia

Authors
 Han Sung Hwang  ;  Young Han Kim  ;  Ja Young Kwon  ;  Yong Won Park 
Citation
 JOURNAL OF PERINATAL MEDICINE, Vol.38(5) : 467-471, 2010 
Journal Title
 JOURNAL OF PERINATAL MEDICINE 
ISSN
 0300-5577 
Issue Date
2010
MeSH
Anemia/complications* ; Anemia/diagnostic imaging* ; Cesarean Section ; Female ; Humans ; Infant, Newborn ; Infant, Small for Gestational Age ; Laser-Doppler Flowmetry ; Male ; Pregnancy ; Pregnancy Complications, Hematologic/diagnostic imaging* ; Pregnancy Outcome ; Pregnancy Trimester, Third ; Premature Birth ; Republic of Korea ; Retrospective Studies ; Ultrasonography, Doppler, Color ; Umbilical Arteries/diagnostic imaging* ; Uterus/blood supply* ; Uterus/diagnostic imaging*
Abstract
AIMS: The aim of this study was to investigate the significance of Doppler ultrasound as a predictor for adverse pregnancy outcomes in Korean women with anemia during the third trimester of pregnancy. METHODS: A retrospective study comparing women with (n=377) and without (n=3183) anemia was performed. Maternal anemia was defined as hemoglobin concentration <10 g/dL. Umbilical artery Doppler (UmA) and uterine artery Doppler (UtA) velocimetry was performed before delivery. RESULTS: There were higher rates of small for gestational age, cesareans for fetal distress, and preterm birth among the anemic compared to non-anemic women. When maternal anemia was combined with abnormal Doppler, the odds ratio (OR) of adverse pregnancy outcome was further increased. Both abnormal UtA and UmA to predict adverse pregnancy outcome showed sensitivity, specificity, positive and negative predictive values of 41.2%, 97.4%, 85.9%, and 51.2%, respectively (OR 2.0; 95% confidence interval 1.2-2.3). CONCLUSIONS: Doppler ultrasound examination could be used as a predictor for adverse pregnancy outcomes in women with anemia during the third trimester.
Full Text
http://www.degruyter.com/view/j/jpme.2010.38.issue-5/jpm.2010.047/jpm.2010.047.xml
DOI
10.1515/jpm.2010.047
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers
Yonsei Authors
Kwon, Ja Young(권자영) ORCID logo https://orcid.org/0000-0003-3009-6325
Kim, Young Han(김영한) ORCID logo https://orcid.org/0000-0003-0645-6028
Park, Yong Won(박용원)
Hwang, Han Sung(황한성)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/102126
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