Cited 5 times in
Effect of primate bone marrow stromal cells on survival and neurite outgrowth
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김긍년 | - |
dc.contributor.author | 오진수 | - |
dc.contributor.author | 윤도흠 | - |
dc.contributor.author | 하윤 | - |
dc.date.accessioned | 2015-04-23T17:14:12Z | - |
dc.date.available | 2015-04-23T17:14:12Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 0959-4965 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/102080 | - |
dc.description.abstract | We tested whether bone marrow stromal cells (BMSCs) could enhance the survival and neurite growth of dorsal root ganglia (DRG) through substrate effects or secreted factors. Our results showed that in DRG with BMSCs and BMSC-conditioned media cultures compared with DRG-fibroblast cultures, there was a significant increase in the number and length of, area covered by, and number of cells with definite neurites. In cytokine assays with conditioned media, vascular endothelial growth factor, granulocyte macrophage colony-stimulating factor, and IL-6 secreted by BMSCs may contribute to observed neurotrophic effects. These findings indicate that BMSCs of adult Macaca fascicularis increased neuronal survival and promoted neurite outgrowth of DRG by means of secretory factors. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 877~881 | - |
dc.relation.isPartOf | NEUROREPORT | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Animals | - |
dc.subject.MESH | Bone Marrow Cells/physiology* | - |
dc.subject.MESH | Cell Count | - |
dc.subject.MESH | Cell Survival/physiology | - |
dc.subject.MESH | Coculture Techniques | - |
dc.subject.MESH | Culture Media, Conditioned | - |
dc.subject.MESH | Cytokines/biosynthesis | - |
dc.subject.MESH | Ganglia, Spinal/cytology | - |
dc.subject.MESH | Immunohistochemistry | - |
dc.subject.MESH | Macaca fascicularis | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Neurites/physiology* | - |
dc.subject.MESH | Stromal Cells/transplantation* | - |
dc.title | Effect of primate bone marrow stromal cells on survival and neurite outgrowth | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Yonsei Biomedical Research Center (연세의생명연구원) | - |
dc.contributor.googleauthor | Keung Nyun Kim | - |
dc.contributor.googleauthor | James D. Guest | - |
dc.contributor.googleauthor | Jin Soo Oh | - |
dc.contributor.googleauthor | William A. Pennant | - |
dc.contributor.googleauthor | Do Heum Yoon | - |
dc.contributor.googleauthor | Yoon Ha | - |
dc.identifier.doi | 10.1097/WNR.0b013e32833da3a6 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00331 | - |
dc.contributor.localId | A02401 | - |
dc.contributor.localId | A02546 | - |
dc.contributor.localId | A04255 | - |
dc.relation.journalcode | J02361 | - |
dc.identifier.eissn | 1473-558X | - |
dc.identifier.pmid | 20683359 | - |
dc.identifier.url | http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00001756-201009150-00006&LSLINK=80&D=ovft | - |
dc.contributor.alternativeName | Kim, Keung Nyun | - |
dc.contributor.alternativeName | Oh, Jin Soo | - |
dc.contributor.alternativeName | Yoon, Do Heum | - |
dc.contributor.alternativeName | Ha, Yoon | - |
dc.contributor.affiliatedAuthor | Kim, Keung Nyun | - |
dc.contributor.affiliatedAuthor | Oh, Jin Soo | - |
dc.contributor.affiliatedAuthor | Yoon, Do Heum | - |
dc.contributor.affiliatedAuthor | Ha, Yoon | - |
dc.citation.volume | 21 | - |
dc.citation.number | 13 | - |
dc.citation.startPage | 877 | - |
dc.citation.endPage | 881 | - |
dc.identifier.bibliographicCitation | NEUROREPORT, Vol.21(13) : 877-881, 2010 | - |
dc.identifier.rimsid | 52711 | - |
dc.type.rims | ART | - |
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