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폐경 전후 여성에서 상완-발목 맥파속도에 영향을 미치는 요인의 비교

Other Titles
 Comparison of Factors Which Influence the Brachial-Ankle Pulse Wave Velocity in Pre- and Postmenopausal Women 
 정찬경  ;  윤보현  ;  서석교  ;  임경진  ;  전영은  ;  양효인  ;  이경은  ;  조시현  ;  최영식  ;  이병석 
 Journal of Korean Society of Menopause (대한폐경학회지), Vol.16(2) : 86-92, 2010 
Journal Title
Journal of Korean Society of Menopause(대한폐경학회지)
Issue Date
Arterial stiffness ; Brachial-ankle pulse wave velocity ; Premenopausal women ; Postmenopausal women
Objectives: The aim of this study was to compare the factors which influence the brachial-ankle pulse wave velocity (baPWV) in pre- and post-menopausal women. We also investigated the association of menopause with arterial stiffness measured by baPWV.

Methods: We performed a retrospective review of 241 postmenopausal women who attended the health promotion center for a routine checkup. Simple and multiple regression analyses were performed to determine the parameters influencing baPWV in pre- and postmenopausal women. Multiple logistic regression analysis was performed to identify the independent parameters related to increased of arterial stiffness.

Results: Multiple regression analysis showed that diastolic blood pressure (DBP; ? = 0.402, P = 0.009) was identified as an independent determinant for baPWV in premenopausal women, and DBP (? = 0.329, P = 0.021) and the neutrophil-to-lymphocyte ratio (NLR; ? = 0.210, P = 0.016) were identified as independent determinants for baPWV in postmenopausal women. The odds ratio (95% CI) of menopause for a high baPWV was 2.666 (1.025∼6.937).

Conclusion: The NLR is associated with arterial stiffness in postmenopausal women. Consequently, inflammation is thought to play a crucial role in increased arterial stiffness in postmenopausal women. Menopause is associated with a high baPWV, suggesting that changes in the concentrations of sex hormones during the menopausal transition may influence arterial stiffness in clinically healthy wo
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1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers
Yonsei Authors
Seo, Seok Kyo(서석교) ORCID logo https://orcid.org/0000-0003-3404-0484
Yang, Hyo In(양효인)
Lee, Kyung Eun(이경은)
Lee, Byung Seok(이병석) ORCID logo https://orcid.org/0000-0001-6001-2079
Lim, Kyung Jin(임경진)
Jeon, Young Eun(전영은)
Cho, Si Hyun(조시현) ORCID logo https://orcid.org/0000-0003-2718-6645
Choi, Young Sik(최영식) ORCID logo https://orcid.org/0000-0002-1157-4822
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