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Relationship between prostate-specific antigen and body mass index according to age: lower prostate-specific antigen in middle-aged overweight and obese Korean men.

Authors
 Yang W.J.  ;  Cheon S.H.  ;  Kim Y.S.  ;  Kim D.J.  ;  Seong D.H.  ;  Song Y.S.  ;  Cho S.Y.  ;  Cho I.R.  ;  Kim S.I.  ;  Kim S.J.  ;  Kim C.I.  ;  Choi Y.D.  ;  Hong S.J.  ;  Im H.k  ;  Cho J.S. 
Citation
 UROLOGIA INTERNATIONALIS, Vol.85(2) : 143-146, 2010 
Journal Title
UROLOGIA INTERNATIONALIS
ISSN
 0042-1138 
Issue Date
2010
MeSH
Adult ; Age Distribution ; Age Factors ; Aged ; Asian Continental Ancestry Group* ; Body Mass Index* ; Down-Regulation ; Humans ; Male ; Middle Aged ; Obesity/blood* ; Obesity/ethnology* ; Overweight/blood* ; Overweight/ethnology* ; Prostate-Specific Antigen/blood* ; Republic of Korea
Keywords
Prostate ; Prostate-specific antigen ; Obesity ; Body mass index ; Age
Abstract
OBJECTIVE: To analyze the relationship between serum prostate-specific antigen (PSA) and body mass index (BMI) according to age in a population of ostensibly healthy Korean men.

PATIENTS AND METHODS: Between 2002 and 2006, data from 13,025 men who visited health promotion centers were evaluated. All men underwent anthropometric measurements and serum PSA determination. The relationship between serum PSA and BMI according to age was analyzed.

RESULTS: The median age was 50.0 years and the median serum PSA level was 0.69 ng/ml. There was no relationship between serum PSA and BMI in the group whose BMI was <23 kg/m(2). The serum PSA showed a significant inverse relationship in those with BMI of ≥23 kg/m(2). However, this finding was only true among 40- to 59-year-old middle aged men and no such relationship between serum PSA and BMI was seen in the older groups (60-79 years of age).

CONCLUSION: Our study revealed serum PSA had a significant inverse relationship with BMI in overweight and obese men aged between 40 and 59 years; however, there was no relationship between serum PSA and BMI in men whose age was older than 60 years.
Full Text
http://www.karger.com/Article/FullText/317037
DOI
10.1159/000317037
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers
Yonsei Authors
Choi, Young Deuk(최영득) ORCID logo https://orcid.org/0000-0002-8545-5797
Hong, Sung Joon(홍성준) ORCID logo https://orcid.org/0000-0001-9869-065X
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/101776
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