Cited 33 times in
Anterior pituitary dysfunction in moderate-to-severe chronic traumatic brain injury patients and the influence on functional outcome.
DC Field | Value | Language |
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dc.contributor.author | 김덕용 | - |
dc.contributor.author | 박윤길 | - |
dc.date.accessioned | 2015-04-23T17:03:29Z | - |
dc.date.available | 2015-04-23T17:03:29Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 0269-9052 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/101742 | - |
dc.description.abstract | OBJECTIVE: The objective of this study is to determine the prevalence of anterior pituitary dysfunction in moderate-to-severe chronic traumatic brain injury (TBI) patients. The investigation of a relationship between pituitary hormonal status and body mass index (BMI) in TBI patients by observing changes in BMI was conducted as well as an assessment of whether there is a difference in functional outcome related to anterior pituitary dysfunction in TBI patients. METHODS: Forty-five TBI patients and 30 normal controls underwent a series of standard endocrine tests for anterior pituitary hormone function. It was studied whether changes in BMI correlated with anterior pituitary hormone levels. This study also compared changes in mini-mental state examination (K-MMSE) and functional independence measure (FIM) scores between patients in the hormone-sufficient and -deficient groups. RESULTS: Anterior pituitary dysfunction was found in 31.1% of TBI patients. Changes in BMI statistically correlated with IGF-1 and basal cortisol levels. A meaningful difference was found between the hormone-sufficient and -deficient groups in light of the K-MMSE and FIM score gains. CONCLUSIONS: These findings strongly suggest that patients who suffer head trauma should be routinely tested for anterior pituitary hormone deficiency. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1330~1335 | - |
dc.relation.isPartOf | BRAIN INJURY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Body Mass Index | - |
dc.subject.MESH | Brain Injuries/physiopathology* | - |
dc.subject.MESH | Brain Injuries/rehabilitation | - |
dc.subject.MESH | Chronic Disease | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Hypopituitarism/physiopathology* | - |
dc.subject.MESH | Hypopituitarism/rehabilitation | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Pituitary Gland, Anterior/metabolism | - |
dc.subject.MESH | Pituitary Gland, Anterior/physiopathology* | - |
dc.subject.MESH | Pituitary Hormones, Anterior/deficiency | - |
dc.subject.MESH | Pituitary Hormones, Anterior/metabolism* | - |
dc.title | Anterior pituitary dysfunction in moderate-to-severe chronic traumatic brain injury patients and the influence on functional outcome. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Rehabilitation Medicine (재활의학) | - |
dc.contributor.googleauthor | Ki Deok Park | - |
dc.contributor.googleauthor | Deog Young Kim | - |
dc.contributor.googleauthor | Ju Kang Lee | - |
dc.contributor.googleauthor | Hee-Seung Nam | - |
dc.contributor.googleauthor | Yoon-Ghil Park | - |
dc.identifier.doi | 10.3109/02699052.2010.506863 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00375 | - |
dc.contributor.localId | A01596 | - |
dc.relation.journalcode | J00390 | - |
dc.identifier.eissn | 1362-301X | - |
dc.identifier.pmid | 20828231 | - |
dc.identifier.url | http://informahealthcare.com/doi/abs/10.3109/02699052.2010.506863 | - |
dc.subject.keyword | Traumatic brain injury | - |
dc.subject.keyword | pituitary dysfunction | - |
dc.subject.keyword | BMI | - |
dc.subject.keyword | functional outcome | - |
dc.contributor.alternativeName | Kim, Deog Young | - |
dc.contributor.alternativeName | Park, Yoon Ghil | - |
dc.contributor.affiliatedAuthor | Kim, Deog Young | - |
dc.contributor.affiliatedAuthor | Park, Yoon Ghil | - |
dc.citation.volume | 24 | - |
dc.citation.number | 11 | - |
dc.citation.startPage | 1330 | - |
dc.citation.endPage | 1335 | - |
dc.identifier.bibliographicCitation | BRAIN INJURY, Vol.24(11) : 1330-1335, 2010 | - |
dc.identifier.rimsid | 46703 | - |
dc.type.rims | ART | - |
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