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Comparison of efficacies between stents for malignant colorectal obstruction: a randomized, prospective study

 Semi Park  ;  Jae Hee Cheon  ;  Jae Jun Park  ;  Chang Mo Moon  ;  Sung Pil Hong  ;  Sang-Kil Lee  ;  Tae Il Kim  ;  Won Ho Kim 
 Gastrointestinal Endoscopy, Vol.72(2) : 304-310, 2010 
Journal Title
 Gastrointestinal Endoscopy 
Issue Date
BACKGROUND: Colonoscopic insertion of a self-expandable metallic stent (SEMS) has been widely performed for the treatment of malignant colorectal obstruction. Different types of stents could influence the efficacy and complication rate of stent use. OBJECTIVE: To compare the efficacy and complication rates between two SEMSs, the uncovered WallFlex stent and the covered Comvi stent. DESIGN: A prospective, randomized study. SETTING: Tertiary-care academic medical center. PATIENTS: Between 2007 and 2009, a total of 151 patients with malignant colorectal obstruction were enrolled. INTERVENTION: Two types of colorectal SEMSs (the uncovered WallFlex stent by Boston Scientific Corp and the newly developed covered Comvi stent by Taewoong Medical Co) were inserted. MAIN OUTCOME MEASUREMENTS: Technical success, clinical success, stent patency, and complication rate according to stent type. RESULTS: Technical failure occurred in 2 patients (1.3%); one was in the WallFlex group and the other in the Comvi group. Clinical failure developed in 9 patients (6.0%): 6 patients from the WallFlex group and 3 from the Comvi group. Complications because of cancer infiltration occurred more frequently in the WallFlex group (14.5% vs 3.8%). However, the rate of stent migration was higher in the Comvi group (21.1% vs 1.8%). The mean patency of the stent did not differ between the two groups (P = .50). LIMITATIONS: This was a single-center study. CONCLUSION: Both uncovered WallFlex and covered Comvi stents were suitable for relieving malignant colorectal obstruction. Tumor ingrowth was more common in the WallFlex group, but stent migration was more common in the Comvi group.
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1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
김원호(Kim, Won Ho) ORCID logo https://orcid.org/0000-0002-5682-9972
김태일(Kim, Tae Il) ORCID logo https://orcid.org/0000-0003-4807-890X
문창모(Moon, Chang Mo)
박세미(Park, Se Mi)
박재준(Park, Jae Jun)
이상길(Lee, Sang Kil) ORCID logo https://orcid.org/0000-0002-0721-0364
천재희(Cheon, Jae Hee) ORCID logo https://orcid.org/0000-0002-2282-8904
홍성필(Hong, Sung Pil)
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