Cited 12 times in
Evaluation of new hemagglutinin-based rapid antigen test for influenza A pandemic (H1N1) 2009
DC Field | Value | Language |
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dc.contributor.author | 김창수 | - |
dc.date.accessioned | 2015-04-23T16:57:17Z | - |
dc.date.available | 2015-04-23T16:57:17Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 1386-6532 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/101547 | - |
dc.description.abstract | BACKGROUND: A new rapid antigen test (RAT), based on hemagglutinin, was developed for the improvement of influenza A pandemic (H1N1) 2009 detection. OBJECTIVE: To evaluate the performance of the new RAT for the diagnosis of influenza A pandemic (H1N1) 2009. STUDY DESIGN: The new RAT included 2009 H1N1 hemagglutinin-based band and influenza A and influenza B nucleoprotein-based bands. During the period from November 24, 2009 to December 14, 2009, 948 patients underwent the new RAT and real-time reverse transcriptase polymerase chain reaction (rRT-PCR) at the same time. The result of the new RAT was compared with that of rRT-PCR, and the results of hemagglutinin-based and nucleoprotein-based antigen tests were compared. RESULT: Among the 260 patients confirmed by rRT-PCR, 153 (58.8%) were positive in the nucleoprotein-based antigen test, and 182 (70.0%) were positive in the hemagglutinin-based antigen test. These results show that the new hemagglutinin-based antigen test was more sensitive than the nucleoprotein-based antigen test for the detection of influenza A pandemic (H1N1) 2009 (p<0.001, the McNemar test). CONCLUSION: The new hemagglutinin-based antigen test improved the sensitivity of diagnosis for influenza A pandemic (H1N1) 2009 and it might be helpful for the diagnosis of influenza A pandemic (H1N1) 2009 | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 69~72 | - |
dc.relation.isPartOf | JOURNAL OF CLINICAL VIROLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adolescent | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Child | - |
dc.subject.MESH | Child, Preschool | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Hemagglutinin Glycoproteins, Influenza Virus*/immunology | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Infant | - |
dc.subject.MESH | Influenza A Virus, H1N1 Subtype/genetics | - |
dc.subject.MESH | Influenza A Virus, H1N1 Subtype/immunology* | - |
dc.subject.MESH | Influenza, Human/diagnosis* | - |
dc.subject.MESH | Influenza, Human/immunology | - |
dc.subject.MESH | Influenza, Human/virology | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Pandemics* | - |
dc.subject.MESH | Predictive Value of Tests | - |
dc.subject.MESH | Reverse Transcriptase Polymerase Chain Reaction | - |
dc.subject.MESH | Sensitivity and Specificity | - |
dc.subject.MESH | Time Factors | - |
dc.subject.MESH | Young Adult | - |
dc.title | Evaluation of new hemagglutinin-based rapid antigen test for influenza A pandemic (H1N1) 2009 | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Preventive Medicine (예방의학) | - |
dc.contributor.googleauthor | Young Keun Kim | - |
dc.contributor.googleauthor | Young Uh | - |
dc.contributor.googleauthor | Jin-Kyong Chun | - |
dc.contributor.googleauthor | Changsoo Kim | - |
dc.contributor.googleauthor | Hyo Youl Kim | - |
dc.identifier.doi | 10.1016/j.jcv.2010.06.012 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01042 | - |
dc.relation.journalcode | J01343 | - |
dc.identifier.eissn | 1873-5967 | - |
dc.identifier.pmid | 20663709 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S1386653210002568 | - |
dc.subject.keyword | Influenza A virus | - |
dc.subject.keyword | H1N1 subtype | - |
dc.subject.keyword | Rapid antigen test | - |
dc.subject.keyword | Reverse transcriptase polymerase chain reaction | - |
dc.subject.keyword | Diagnosis | - |
dc.contributor.alternativeName | Kim, Chang Soo | - |
dc.contributor.affiliatedAuthor | Kim, Chang Soo | - |
dc.citation.volume | 49 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 69 | - |
dc.citation.endPage | 72 | - |
dc.identifier.bibliographicCitation | JOURNAL OF CLINICAL VIROLOGY, Vol.49(1) : 69-72, 2010 | - |
dc.identifier.rimsid | 47808 | - |
dc.type.rims | ART | - |
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