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Characteristics of complex fractionated atrial electrogram in the electroanatomically remodeled left atrium of patients with atrial fibrillation

Authors
 Jae Hyung Park  ;  Sang Weon Park  ;  Jong Youn Kim  ;  Sook Kyoung Kim  ;  Boyoung Jeoung  ;  Moon-Hyung Lee  ;  Chun Hwang  ;  Young-Hoon Kim  ;  Sung Soon Kim  ;  Hui-Nam Pak 
Citation
 Circulation Journal, Vol.74(8) : 1557-1563, 2010 
Journal Title
 Circulation Journal 
ISSN
 1346-9843 
Issue Date
2010
Abstract
BACKGROUND: Complex fractionated atrial electrogram (CFAE) guided ablation is effective in some patients with persistent atrial fibrillation (PeAF), but the pattern of CFAE may be different in the remodeled left atrium (LA). METHODS AND RESULTS: In 100 AF patients (83 males, 55.0+/-10.6 years old) with AF (51 paroxysmal AF (PAF), 49 PeAF) who underwent catheter ablation, CFAE cycle length (CL) and distribution (NavX 3D map) were compared according to the LA volume (3D-CT) and endocardial voltage (during high right atrial pacing 500-ms (Vol(PACE)) and AF (Vol(AF); NavX). The mean CFAE-CL was longer (P=0.003) and the % area CFAE was smaller (P=0.006) in patients with LA >or=125 ml than those with <125 ml. The mean CFAE-CL was longer in patients with Vol(PACE) <1.7 mV than those with >or=1.7 mV (P=0.002) and in Vol(AF) <0.7 mV than >or=0.7 mV (P<0.001). The % area CFAE was smaller in patients with Vol(PACE) <1.7 mV than those with >or=1.7 mV (P=0.006). The incidence of septal CFAE was consistently high, regardless of the degree of LA remodeling. CONCLUSIONS: In the AF patients with an electroanatomically remodeled LA, the % area of CFAE was smaller and mean CFAE-CL was longer than in those with a less remodeled LA. However, the majority of CFAE are consistently positioned on the septum in the remodeled LA.
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DOI
10.1253/circj.CJ-10-0048
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
김성순(Kim, Sung Soon)
김종윤(Kim, Jong Youn) ORCID logo https://orcid.org/0000-0001-7040-8771
박희남(Pak, Hui Nam) ORCID logo https://orcid.org/0000-0002-3256-3620
이문형(Lee, Moon Hyoung) ORCID logo https://orcid.org/0000-0002-7268-0741
정보영(Joung, Bo Young) ORCID logo https://orcid.org/0000-0001-9036-7225
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/101518
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